Sökning: "neonatal cholestasis"

Hittade 5 avhandlingar innehållade orden neonatal cholestasis.

  1. 1. Cholestasis in infants at risk

    Författare :Jonas Teng; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cholestasis is a condition when bile flow from the liver to the intestines is impaired. Unresolved, it may lead to liver transplantation or death. Overall, it affects 1 out of 2500 term infants, but is far more common in high-risk infants with other conditions such as prematurity and hemolytic disease of the fetus and newborn (HDFN). LÄS MER

  3. 2. Neonatal cholestasis : clinical and aetiological aspects, with special reference to viral infections transmitted from mother to infant

    Författare :Björn Fischler; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :neonatal cholestasis; biliary atresia; progressive familial intrahepatic cholestasis; vertical transmission; CMV; HCV; GBV-C HGV;

    Sammanfattning : Although the list of possible causes for neonatal cholestasis is long, in many cases the aetiology remains unknown. The aim of this thesis was to examine the pathogenetic role of viral infections in the early infantile cholestasis. LÄS MER

  4. 3. Progressive familial intrahepatic cholestasis : clinical, biochemical, genetic and histopathological aspects

    Författare :Henrik Arnell; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Progressive familial intrahepatic cholestasis PFIC ; genetic linkage analysis; ABCB11; immunohistochemistry; partial external biliary diversion PEBD ; nuclear scintigraphy; fibrosis; histological regress;

    Sammanfattning : In the early 1980's, most cases of neonatal cholestasis (often referred to as neonatal hepatitis) remained unexplained. By today, many of these diseases have been characterized in detail. LÄS MER

  5. 4. Posterior ocular malformations in children : teratological aspects

    Författare :Kristina Teär Fahnehjelm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Teratology; ocular malformations; visual impairment; anti-epileptic drugs; congenital infection; optic nerve hypoplasia; coloboma; magnetic resonance imaging; neonatal cholestasis; dried blood spots;

    Sammanfattning : Posterior ocular malformations are common causes of visual impairment in Swedish children. The most frequent diagnoses within this group are optic nerve hypoplasia and optic nerve/chorioretinal coloboma. Genetic factors, teratogens like medical/addictive drugs or congenital infections and unknown factors may cause these malformations. LÄS MER

  7. 5. Severe and moderate alpha-1-antitrypsin deficiency at the age of 30

    Författare :Elisabeth Bernspång; allergologi och palliativ medicin Lungmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cohort; screening; alpha-1-antitrypsin; lung function; CT densitometry; liver;

    Sammanfattning : Alpha-1-antitrypsin (AAT) is a glycoprotein synthesised in the liver. Its main role is to protect lung tissue from destruction by neutrophil elastase. In severe (PiZZ) AAT deficiency, there is an increased risk of emphysema, especially in smokers. LÄS MER