Sökning: "neoadjuvant therapy"

Visar resultat 1 - 5 av 41 avhandlingar innehållade orden neoadjuvant therapy.

  1. 1. Endosonography and pretreatment tumor profiling - from sampling, staining, to sequencing

    Författare :Per Hedenström; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endosonography; fine-needle biopsy; pancreatic neoplasms; gastrointestinal stromal tumors; KIT; PDGFRA; Ki-67; imatinib; neoadjuvant therapy;

    Sammanfattning : Background and aims: Endosonography-guided fine needle aspiration (EUS-FNA) is imperfect in diagnosing solid pancreatic lesions (SPL) and subepithelial lesions (SEL) including gastrointestinal stromal tumors (GIST). In GISTs, imatinib therapy is effective only in variants of oncogenes KIT and PDGFRA. LÄS MER

  3. 2. Gastrointestinal stromal tumours. On diagnosis and treatment

    Författare :Per Bümming; Göteborgs universitet; []
    Nyckelord :adjuvant; epidemiology; GIST; imatinib; KIT; mutation; neoadjuvant; neuroendocrine phenotype; PET; prognosis; surgery; vesicle proteins;

    Sammanfattning : Gastrointestinal stromal tumours (GIST) are thought to originate from the interstitial cells of Cajal, which show many properties in common with neurons of the gastrointestinal tract. High-risk GIST has a very poor prognosis and tumour recurrence is common after intentionally curative surgery. LÄS MER

  4. 3. Cardiopulmonary adaption to one-lung ventilation and neoadjuvant therapy during treatment of esophageal cancer

    Författare :Mikael Lund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Introduction: Esophagectomy is the main form of curative treatment for esophageal cancer and has a high morbidity rate. Neoadjuvant chemo- (CT) or chemoradiotherapy (CRT) is employed to increase long-term survival. To improve perioperative care the effects of measures taken to improve surgical exposure i.e. LÄS MER

  5. 4. Aspects of neoadjuvant therapy in the curative treatment of cancer in the esophagus or gastroesophageal junction

    Författare :Fredrik Klevebro; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Malignant esophageal tumors are among the most severe cancers. Only about 30% of the patients are suitable for curative treatment at diagnosis. The treatment is extremely demanding and unfortunately has disappointing results. The staging of disease and the treatment for cancer of the esophagus and gastroesophageal junction need to be improved. LÄS MER

  7. 5. Head and Neck Cancer: Studies on microvessel density, radiation response and FDG PET

    Författare :Eva Brun; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; positron emission tomography PET ; 2-18 fluoro deoxy glucose FDG ; radiotherapy; microvessel density; Head and neck cancer; therapy response; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Sammanfattning : Treatment options of head and neck squamous cell carcinoma (HNSCC) usually include combinations of radiotherapy and surgery, and in some cases addition of chemotherapy. In locally advanced cases cure rates are low. Current prognostic factors cannot foresee the outcome for the individual patient. LÄS MER