Sökning: "necrosis"

Visar resultat 6 - 10 av 436 avhandlingar innehållade ordet necrosis.

  1. 6. Tumor necrosis factor-a in atherosclerosis

    Författare :Stefan Jovinge; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :atherosclerosis; oxidized low-density lipoprotein; monocytes; tumor necrosis factor-a; cytokinesis; ets-l; matrix metalloproteinases; apoptosis; glucose metabolism; insulin resistance; myocardial infarction;

    Sammanfattning : The presence of inflammatory cells is prominent at all phases of the atherosclerotic process leaving no doubt that the inflammation is of central importance in atherosclerosis. The recruitment of inflammatory cells into the vessel wall is therefore a key event in early lesion formation. LÄS MER

  2. 7. Proton trapping in the cellular acidic vacuolar compartment : lysosomal mechanisms in apoptosis/necrosis and iron chelation

    Författare :Zhengquan Yu; Anders Isaksson; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Under ischemic conditions, a number of cytotoxic metabolic products are formed. Reactive oxygen species are known to be important mediators of progressive ischemic cell injury, and the synergistic damage to cells caused by the combination of such oxygen species and redox-active iron is well appreciated. LÄS MER

  3. 8. Infectious Pancreatic Necrosis Virus (IPNV) - Structural Studies and Methodology

    Författare :Linda Eliasson; Molekylär cellbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi; Microbiology; VP2; Glycosylation; Immuno dot blot; IPNV; TCID50;

    Sammanfattning : Infectious pancreatic necrosis virus (IPNV) is a Birnavirus that infects salmonid fish. The infection is usually mortal for fish under six months of age, while older fish become carriers, usually without any signs of infection, and will spread the virus to other susceptible fish and to their offspring. LÄS MER

  4. 9. Structural and functional analyses of infectious pancreatic necrosis virus (IPNV)

    Författare :Anna Hjalmarsson; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cellular localisation; glycosylation; VP3-RNA cores; virus-specified components; immuno dot blot; TCID50; IPNV; purification; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Infectious pancreatic necrosis virus (IPNV) is a naked virus of an uncomplicated structure. In the interior part of the virion, the two segments of double-stranded RNA are located together with the minor structural protein VP1. This protein is detected in its free form as well as linked to the genome. LÄS MER

  5. 10. Internal fixation of femoral neck fractures

    Författare :Leif Hernefalk; Linköpings universitet; []
    Nyckelord :Femoral neck fracture; osteotomy; internal fixation; device; technical principles; scintimetry; radiography; biomechanics; malposition; malreduction; complications; bone necrosis; revascularization; segmental collapse; non-union; elderly; osteoporosis; MEDICINE; MEDICIN;

    Sammanfattning : The incidence of femoral neck fractures in elderly people is rising requiring large health care resources. Internal fixation of the fracture is the treatment of choice in Scandinavia, but in 20-40% of the cases a late complication such as a segmental collapse of the femoral head after initial bone necrosis, or a non-union of the fracture because of non-healing, will occur. LÄS MER