Sökning: "myoblast"

Visar resultat 1 - 5 av 16 avhandlingar innehållade ordet myoblast.

1. 1. Cell therapy for denervated tissue

   Författare :Roine El-Habta; Ludvig J. Backman; Paul J. Kingham; Patrik Danielson; António Salgado; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipose tissue-derived stem cell; cell therapy; denervation; differentiation; myoblast; peripheral nerve injury; proliferation; regeneration; skeletal muscle; stromal vascular fraction; survival; tendon; cellforskning; cell research; Medical Cell Biology; medicinsk cellbiologi;

   Sammanfattning : Background: Peripheral nerve injury results in denervation of tendons and muscles. The biology of denervated muscle has been well studied but little is known about the associated tendons. LÄS MER

3. 2. Cellular studies of neuromuscular disorders related to the sarcomeric proteins

   Författare :Saba Abdul-Hussein; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; myogenesis; myoblast; sarcomeric myopathy; TPM2; TRIM54; TRIM63;

   Sammanfattning : Sarcomere is the basic unit of cardiac and skeletal muscle contraction and its proper function requires an invariant organization of this structure. Mutations in sarcomeric proteins are known to cause increasing number of different cardiac and skeletal muscle diseases. LÄS MER

4. 3. Animal genomics – gene discovery and gene characterization

   Författare :Rakan Naboulsi; Leif Andersson; Mårten Larsson; Susanne Kerje; Tosso Leeb; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Spontaneous autoimmune thyroiditis; SAT; Hashimoto’s thyroiditis; HT; Obese strain; transcriptional regulation; ZBED6; Igf2; miRNA; miR483; Whole-genome sequencing; RNA-seq; miRNA-seq;

   Sammanfattning : This thesis involves two projects. The aim in the first project was to identify genomic regions associated with spontaneous autoimmune thyroiditis (SAT), which is a hereditary autoimmune disease that affects the obese strain (OS) of chicken, an animal model for human Hashimoto’s thyroiditis (HT). LÄS MER

5. 4. Effects of virus infection and interferon-y on the development of the neuromuscular junction in vitro

   Författare :Sofija Kelic; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Normal development of the nervous system depends upon complex interactions between cells and their local environment. These interactions may be disturbed by toxic and infectious agents. It is well known that such agents can cause malformations, due to interference with neural tube formation or neuronal proliferation and migration. LÄS MER

7. 5. Multifaceted roles of the transmembrane nuclear envelope protein, Samp1

   Författare :Mohammed Hakim Jaffer Ali; Einar Hallberg; Giovanna Lattanzi; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Nuclear envelope; transmembrane protein interaction studies; cell differentiation; stem cells; myopathies; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Sammanfattning : The eukaryotic nuclear envelope (NE), separates the nucleoplasm from cytoplasm and is made up of two concentric lipid membranes, the outer and the inner nuclear membranes (ONM and INM), the nuclear pore complexes (NPCs) and an underlying filamentous nuclear lamina. The INM contains hundreds of unique transmembrane proteins of which only a handful have been characterized. LÄS MER