Sökning: "myeloid cell"

Visar resultat 11 - 15 av 316 avhandlingar innehållade orden myeloid cell.

  1. 11. Molecular Mechanisms in Hematopoietic Stem Cell Aging

    Författare :Gudmundur Norddahl; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The blood is composed of many different cell types that through tightly regulated mechanisms are derived from hematopoietic stem cells (HSCs). In addition, HSCs are able to undergo self-renewing divisions whereby new HSCs are produced. LÄS MER

  3. 12. Cancer and cancer stem cell targeting agents : A focus on salinomycin and apoptin

    Författare :Jaganmohan Reddy Jangamreddy; Marek Los; Karin Roberg; Anna-Lotta Hallbeck; Boris Zhivotovsky; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Current cancer treatments involving surgery, radiotherapy, and chemotherapy target the vast majority of cancer cells, but they are only partially effective in eliminating the disease. Failure to eliminate cancer with conventional treatments can lead to recurrence, which usually kills patient. LÄS MER

  4. 13. FLT3 receptor in normal and malignant hematopoiesis

    Författare :Shabnam Kharazi; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FLT3-ITD; FLT3; lineage commitment; acute myeloid leukemia; myeloprolifetaive disease; hematopoietic stem cell;

    Sammanfattning : All hematopoietic cells originate from hematopoietic stem cells (HSCs) residing in the bone marrow (BM). The classical model of hematopoietic lineage commitment, that has been the prevailing model for hematopoiesis, proposes that the first lineage commitment step of HSCs and progenitors results in a strict separation of myelopoiesis and lymphopoiesis. LÄS MER

  5. 14. To be or not to be, unraveling molecular mechanisms for lineage decisions in developing blood cells

    Författare :Robert Månsson; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellular fluids; Haematology; common lymphoid precursor CLP ; early B-cell factor 1 EBF1 ; B-cell; Stemcell; hematopoiesis; extracellulära vätskor; Immunology; serology; transplantation; Immunologi; serologi;

    Sammanfattning : All hematopoietic cells originate from hematopoietic stem cells (HSC) residing in the BM. The process of differentiation, through which HSCs generate progenitors and subsequently mature blood cells has been extensively studied but many of the regulatory mechanisms involved remains elusive. LÄS MER

  7. 15. On the origin of B cells. Elucidating the Role of Tyrosine Kinase Receptors in B Cell Development

    Författare :Alya Zriwil; Avdelningen för molekylär hematologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoiesis; B cell development; cytokine; tyrosine kinase receptors;

    Sammanfattning : B cells are essential cells that are part of the adaptive immune system with the capacity to produce antibodies against exogenous antigens. These cells are produced through a process called hematopoiesis, tightly regulated by extrinsic and intrinsic factors. LÄS MER