Sökning: "myelination"

Visar resultat 1 - 5 av 26 avhandlingar innehållade ordet myelination.

1. 1. Lithium and brain plasticity - studies on glial cell changes and electroconvulsive treatment-induced amnesia in rats

   Författare :Karin Orre; Enheten för psykiatrisk neuromodulering (PNU); []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lithium; electroconvulsive seizures; mood disorder; gliogenesis; amnesia; oligodendrogenesis; myelination; NG2 cells;

   Sammanfattning : Depression and bipolar disorder, collectively known as mood disorders, are devastating, common and often chronic illnesses. Imaging studies of patients with mood disorders have demonstrated structural changes in several brain regions implicated in mood regulation. LÄS MER

3. 2. On laminins and laminin receptors and their roles in regeneration and myelination of the peripheral nerve

   Författare :Wilhelm Wallquist; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Motoneuron; dorsal root ganglion neuron; integrin; laminin; Schwann cell; Sciatic nerve; regeneration; myelination; in situ hybridization; immunohistochemistry and electron microscopy.;

   Sammanfattning : One important prerequisite for successful axon regeneration is that appropriate extracellular molecules are available for outgrowing axons and that receptors for such molecules are found in the regenerating neuron. Laminin associated integrin subunits alpha3, alpha6, alpha7 and beta1 mRNAs are here shown to be present in rat motoneurons, and in the case of integrin subunits alpha7 and gamma1, also immunohistochemical (IHC) labelling of the proteins was demonstrated. LÄS MER

4. 3. Molecular studies of hypothalamic food intake regulating systems and central myelination in two anorectic mouse models

   Författare :Ulrika Bergström; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The aim of this thesis is to increase the understanding of the hypothalamic mechanisms that are vital for food intake regulation, in particular as it relates to anorexia, and the molecular mechanisms underlying myelination and nodal/paranodal domain organization. The majority of the thesis concerns the anorectic phenotype of two mouse models for which we have found both great similarities and differences pointing to different mechanisms generating similar symptoms and neuropeptidergic alterations. LÄS MER

5. 4. On the relation between nerve fibres and glial cells

   Författare :Carl Bjartmar; W. F. Blakemore; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : The general aim of this study is to generate knowledge on the normal axo-glial relations in developing and adult vertebrate white matter. CNS and PNS specimens from developing and mature rats and from chickens of various ages were analysed through electron microscopy of single and serial sections, or through immunohistochemistry. LÄS MER

7. 5. Neuron-glial Interaction in the Developing Peripheral Nervous System

   Författare :Mikael Corell; Åsa Fex Svenningsen; Klas Kullander; Helgi Schöith; Heape Anthony; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Schwann cell; nonmyelinating Schwann cell; myelinating Schwann cell; development; proliferation; differentiation; myelin; neural stem cell; central nervous system; peripheral nervous system; enteric nervous system; N-cadherin; GABA; GAD; GABA B receptor; baclofen; CGP55485; Neuroscience; Neurovetenskap; Neuroscience; Neurovetenskap;

   Sammanfattning : The nervous system, including the brain, is the most sophisticated organ in the mammalian body. In such a complex network, neuron-glial interaction is essential and controls most developmental processes, such as stem cell fate determination, migration, differentiation, synapse formation, ensheathment and myelination. LÄS MER