Sökning: "myelinating"
Visar resultat 1 - 5 av 14 avhandlingar innehållade ordet myelinating.
1. Neuron-glial Interaction in the Developing Peripheral Nervous System
Sammanfattning : The nervous system, including the brain, is the most sophisticated organ in the mammalian body. In such a complex network, neuron-glial interaction is essential and controls most developmental processes, such as stem cell fate determination, migration, differentiation, synapse formation, ensheathment and myelination. LÄS MER
2. Demyelinating conditions regulated by ROS pathways outside and inside the brain
Sammanfattning : Multiple sclerosis (MS) is a chronic inflammatory condition of the central nervous system with immune-mediated damage on myelinated nerve tracts. Accumulating evidence support a role for autoreactive T-lymphocytes orchestrating immuneattacks on myelinating oligodendrocytes (OLs). LÄS MER
3. Fate selection in the neural crest lineage and its regulation
Sammanfattning : The neural crest is a transient embryonic progenitor cell population that generates a diverse array of cell and tissue types, including cartilage, bone, teeth, soft connective and adipose tissues, peripheral sensory and autonomic neurons, myelinating and non-myelinating Schwann cells, melanocytes, cardiac outflow tract, adrenal medulla and other derivatives. Neural crest cells start as neuroepithelial cells forming at the border of neural and non-neural ectoderm in a vertebrate embryo. LÄS MER
4. Clusterin and Megalin in The Spinal Cord
Sammanfattning : Nerve injury induces up-regulation of the chaperone protein clusterin in affected neurons and adjacent astrocytes but the functional significance of this response is unclear. We find that motor neuron survival is significantly greater in clusterin(+/+) compared to (-/-) mice. LÄS MER
5. Discovering cell-type dynamics in the nervous system by single-cell transcriptomics
Sammanfattning : The mammalian nervous system is arguably the most intricate system known to science. At its basis lie highly specialized single cells, specifically interacting to ensure everything from normal functionality to complex behavior and cognition. LÄS MER