Sökning: "muscarinic receptor"
Visar resultat 1 - 5 av 64 avhandlingar innehållade orden muscarinic receptor.
1. Muscarinic receptors and urinary bladder selectivity : Properties that determine the organ selectivity of compounds
Sammanfattning : Urinary bladder contraction is mainly mediated by activation of muscarinic acetylcholine receptors (mAChR). Muscarinic antagonists are often effective in treatment of unstable bladder. The effectiveness of this treatment has often been limited by side effects as dry mouth. LÄS MER
2. Muscarinic Receptors in the Urinary Bladder - The role of the urothelium regarding cholinergic and nitrergic effects in inflammation
Sammanfattning : Inflammation alters the functional properties of the urinary bladder. Interstitial cystitis (IC) is a chronic inflammatory syndrome in man that is characterized by urgency, frequency and visceral pain. LÄS MER
3. Spinal Acetylcholine Release : Mechanisms and Receptor Involvement
Sammanfattning : Impulses coming from peripheries are modified in the spinal cord and transmitted to the brain. Several neurotransmitters have been involved in the processing of impulses in the spinal dorsal horn. Acetylcholine (ACh) is one of many neurotransmitters involved in the regulation of nociception in the spinal cord. LÄS MER
4. Muscarinic acetylcholine receptors : investigation of interactions with agonists and antagonists
Sammanfattning : In the present investigation interactions of agonists and antagonists with the muscarinic acetylcholine receptor from rat cerebral cortex and rat ileum smooth muscle have been characterized.It is suggested that the binding of antagonist involves two sequential equilibria, an association reaction followed by isomerization of the receptor-antagonist complex. LÄS MER
5. Investigation on Pre- and Postsynaptic Ca2+ Signaling in Neuronal Model Systems
Sammanfattning : Communication between neuronal and non-neuronal is called volume transmission when the released neurotransmitter (NT) acts via diffusion and affects several target cells. Both the neurosecretory and postsynaptic cell responses are linked to [Ca2+]i elevations. LÄS MER