Sökning: "multivariate concentric square field"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden multivariate concentric square field.

  1. 1. Individual differences in behavior, neurochemistry and pharmacology associated with voluntary alcohol intake

    Författare :Shima Momeni; Erika Roman; Bo Söderpalm; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intermittent access; multivariate concentric square field; open field; risk assessment; risk taking; individual difference; behavior; strain variation; endogenous opioid system; naltrexone; Pharmaceutical Science; Farmaceutisk vetenskap;

    Sammanfattning : Alcohol use disorder is a worldwide public health problem and is a disorder with substantial individual variation. There are suggested links between various behavioral traits, comorbid psychiatric diseases and excessive alcohol consumption. LÄS MER

  3. 2. Early Environment, Adolescent Alcohol Drinking and Neurobiological Responses to Drugs

    Författare :Sara Palm; Ingrid Nylander; Anne-Lie Svensson; Lundblad Martin; Giancarlo Colombo; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adolescence; beta-endorphin; dopamine; dynorphin; endogenous opioids; enkephalin; high-speed chronoamperometry; housing conditions; maternal separation; multivariate concentric square field™ test; open field test; radioimmunoassay; voluntary alcohol intake; Wistar rats; Pharmaceutical Science; Farmaceutisk vetenskap;

    Sammanfattning : Genes and environment interact to determine an individual’s vulnerability or resilience to several psychiatric disorders, including alcohol use disorder (AUD). Alcohol use is often initiated during adolescence and early onset drinking is associated with increased risk for later AUD. LÄS MER

  4. 3. Examining Female Resilience to Early Environmental Influences : Short- and long-term consequences on behaviour, HPA axis activity and alcohol intake after prolonged maternal separation

    Författare :Stina Lundberg; Erika Roman; Ingrid Nylander; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adolescence; Adulthood; Corticosterone; Early-life stress; Handling; Maternal deprivation; Multivariate concentric square field; MCSF; Sex differences; Social play behavior; Stress reactivity; Supplier differences; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : Early-life experiences are an important factor influencing further development of the individual. Adverse experiences early in life, such as various kinds of abuse or neglect, are types of early-life stress that can adversely affect an individuals health, as well as contribute to the development of an array of disorders later in life. LÄS MER

  5. 4. Strategies in the rat gambling task : Individual differences in decision-making and associations to behavior, neurobiology and human strategies

    Författare :Nikita Tjernström; Erika Roman; Barry Everitt; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Behavior; copulatory test; decision-making; ethanol; gambling disorder; impulsivity; individual differences; Iowa gambling task; MALDI-MSI; multivariate concentric square field; neurobiology; novel cage; opioid antagonist; rat gambling task; resting-state fMRI; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : Gambling disorder (GD) is a behavioral addiction characterized by persistent and recurrent gambling behavior that disrupts personal, social or professional life. Studies have revealed that GD shares many features with alcohol and substance use disorders, but little is known about potential unique features in GD and to what extent characteristics are shared. LÄS MER

  7. 5. Anabolic Androgenic Steroids : Neurobiological Effects of Nandrolone, Testosterone, Trenbolone, and Stanozolol

    Författare :Sofia Zelleroth; Mathias Hallberg; Astrid Bjørnebekk; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anabolic androgenic steroids; testosterone; nandrolone; trenbolone; stanozolol; central nervous system; primary cortical cell cultures; rats; multivariate concentric square field; novel object recognition.; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : The use of anabolic androgenic steroids (AAS) for recreational purposes is a health concern, as long-term AAS-use in supraphysiological doses is associated with severe physical and psychological adverse effects. Several behavioral and cognitive problems are reported after long-term AAS-use, and alterations in brain morphology as well as neurotransmitter systems have been reported. LÄS MER