Sökning: "multivariable systems"

Visar resultat 21 - 25 av 60 avhandlingar innehållade orden multivariable systems.

  1. 21. THE VASOPRESSIN SYSTEM IN DIABETES MELLITUS, OBESITY AND THE METABOLIC SYNDROME

    Författare :Sofia Enhörning; Kardiovaskulär forskning - hypertoni; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; arginine vasopressin; copeptin; prediction; epidemiology; diabetes mellitus; risk factors; abdominal obesity; obesity; metabolic syndrome; microalbuminuria; AVPR1A; AVPR1B;

    Sammanfattning : Background: Animal studies suggest that the arginine vasopressin (AVP) system plays a role in glucose and fat metabolism, but data from humans are limited. Method and results: We analysed plasma copeptin (copeptin), a stable C-terminal fragment of the AVP pro-hormone in the large, Swedish, population-based cohort Malmö Diet and Cancer Study Cardiovascular Cohort (MDC-CC, n=6103). LÄS MER

  3. 22. Acute coronary syndrome : bleeding, platelets and gender

    Författare :Anna Holm; Eva Swahn; Joakim Alfredsson; Sofia Sederholm Lawesson; Christina Christersson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : BACKGROUNDBleeding complications increase mortality in patients with acute coronary syndrome (ACS). Potential gender difference in bleeding regarding prevalence, location, severity and prognostic impact is still controversial and not well investigated. In regard to this aspect the relevance of triple antithrombotic therapy (TAT) is questioned. LÄS MER

  4. 23. Symptomatic Carotid Stenosis - optimal timing of surgical treatment

    Författare :Sofia Strömberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; carotid endarterectomy; carotid artery stenosis; stroke; transient ischemic attack; ocular transient ischemic attack;

    Sammanfattning : Abstract In patients with symptomatic carotid artery stenosis is convincing evidence that carotid endarterectomy (CEA) confers maximum benefit if performed within 14 days from index event. Patients with TIA or minor stroke have an increased risk of early recurrent stroke in the first weeks after the index event, then declining over months. LÄS MER

  5. 24. Emerging biomarkers in cardiometabolic disease

    Författare :John Molvin; Kardiovaskulär forskning - hypertoni; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diabetes mellitus; type 2; Biomarker discovery; Cardiometabolic disease; cardiometabolic biomarkers; CVD; galectin 4; Olink;

    Sammanfattning : AbstractThe epidemiological association between diabetes and heart failure is well-established and the two entities areemerging as global threats, both individually and synergistically, to an aging population. The exploration of multipleproteins can shed light on pathophysiological pathways in both diabetes and cardiovascular disease. LÄS MER

  7. 25. Bridging the gap between clinical trials and clinical practice : sacubitril-valsartan in heart failure as a model

    Författare :Helena Norberg; Krister Lindmark; Ellinor Bergdahl; Eva-Lotta Glader; Björn Wettermark; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systematic implementation; healthcare quality improvement; chronic disease management; heart failure; sacubitril-valsartan; real-world population; sex differences; kardiologi; Cardiology;

    Sammanfattning : When novel treatments prove more effective than standard therapies, a swift and effective implementation is needed to reach cost-effectiveness and to benefit eligible patients. Meanwhile, women and elderly are often under-represented in clinical trials, which creates a knowledge gap on how to optimize treatment in clinical practice. LÄS MER