Sökning: "multiple sclerosis karolinska"

Visar resultat 1 - 5 av 191 avhandlingar innehållade orden multiple sclerosis karolinska.

  1. 1. Quantitative MRI Biomarkers of Neurodegeneration in Multiple Sclerosis

    Författare :Michael Platten; Tobias Granberg; Chunliang Wang; Fredrik Piehl; Sara Shams; Mattias Vågberg; KTH; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Machine learning; Multiple sclerosis; Corpus callosum; Neurodegeneration; Medical Technology; Medicinsk teknologi;

    Sammanfattning : Background: Multiple sclerosis (MS) is a chronic neuroinflammatory and neurodegenerative disease that targets myelin in the brain and spinal cord. The corpus callosum connects the cerebral hemispheres and is composed of heavily myelinated axons. LÄS MER

  3. 2. Immunogenetic studies of multiple sclerosis

    Författare :Arturs Ligers; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Multiple sclerosis; CTLA-4; HLA-A2; HLA-A3; HLA-DRB1*15; HLA-DRB1*;

    Sammanfattning : Multiple sclerosis (MS) is an inflammatory, demyelinating and neurodegenerative disease of the central nervous system (CNS). Several genetic factors are likely to be of importance for MS rather than one factor. LÄS MER

  4. 3. Insights from comorbidity into multiple sclerosis aetiology and outcomes

    Författare :Homayoun Roshanisefat; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Multiple Sclerosis;

    Sammanfattning : Aim: The overall aim of this research was to investigate the nature of the comorbidities in multiple sclerosis (MS) in four large population-based studies. The first study assessed whether the diagnosis underlying appendicectomy is a useful marker of MS risk. LÄS MER

  5. 4. Tobacco and multiple sclerosis susceptibility

    Författare :Anna Karin Hedström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system (CNS) that arises from a combination of a complex genetic predisposition and environmental factors. For northern Europeans, the lifetime risk of MS is 1:400, making it the most common non-traumatic cause of disability in young adults. LÄS MER

  7. 5. HLA genetics in multiple sclerosis

    Författare :Jenny Link; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple sclerosis (MS) is a chronic disease in which both genetic and environmental risk factors contribute to disease susceptibility. MS patients suffer from inflammatory lesions in the central nervous system which results in demyelination of nerve cells, reduced neuronal activity and finally neurodegeneration. LÄS MER