Sökning: "multiple myeloma"
Visar resultat 11 - 15 av 88 avhandlingar innehållade orden multiple myeloma.
11. Genetic analyses of multiple myeloma and related plasma cell dyscrasias
Sammanfattning : Acquired genetic changes have proved to be of diagnostic and prognostic importance in different hematologic malignancies as well as in some solid tumor types. However, although multiple myeloma (MM), an incurable disease, and its proceeding stage monoclonal gammopathy of undetermined significance (MGUS) are quite common, little is known about the karyotypic features of these plasma cell dyscrasias. LÄS MER
12. Tumour Survival Signals and Epigenetic Gene Silencing in Multiple Myeloma : Implications for Biology and Therapy
Sammanfattning : This thesis is focused on multiple myeloma (MM), a haematological malignancy that still remains incurable. The pathogenesis of MM is not fully understood and there is a large intra-tumour and interclonal genetic variation in MM patients. LÄS MER
13. Clinical studies in multiple myeloma
Sammanfattning : Multiple Myeloma (MM) is an incurably disease of the bone marrow. It is characterized by the uncontrolled growth of clonal plasma cells (PCs) and leads to production of non-functional gammaglobulin. Clinical features include loss of normal bone marrow function, defect bone structure and kidney failure. LÄS MER
14. Neutrophils as Suppressor Cells and their role in Multiple Myeloma
Sammanfattning : .... LÄS MER
15. Identification and characterization of DNA sequence variants associated with multiple myeloma
Sammanfattning : Multiple myeloma (MM) is the second most common hematologic malignancy. The disease is characterized by an uncontrolled growth of malignant plasma cells in the bone marrow, producing a monoclonal immunoglobulin (“M protein”) that can be detected in peripheral blood. LÄS MER