Sökning: "multipel skleros"

Visar resultat 1 - 5 av 26 avhandlingar innehållade orden multipel skleros.

  1. 1. Environmental risk factors for multiple sclerosis

    Författare :Jonatan Salzer; Peter Sundström; Kjell-Morten Myhr; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Multiple sclerosis; risk factors in epidemiology; prospective; month of birth; vitamin D; vitamin A; C-reactive protein; hygiene hypothesis; smoking; cotinine; Epstein-Barr virus; Epidemiology; epidemiologi;

    Sammanfattning : Background Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system. It usually strikes during young adulthood, and 2.5 million individuals are estimated to have the disease worldwide. LÄS MER

  3. 2. Hematopoietic Stem Cell Transplantation for Treatment of Multiple Sclerosis in Sweden

    Författare :Christina Zjukovskaja; Joachim Burman; Kim Kultima; Susanna Brauner; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AHSCT; HSCT; hematopoietic stem cell transplantation; multiple sclerosis; RRMS; inflammation; biomarkers; АТГСК; ТГСК; Трансплантация гемопоэтических стволовых клеток; рассеянный склероз; воспаление; биомаркеры; AHSCT; HSCT; Hematopoetisk stamcellstransplantation; multipel skleros; RRMS; inflammation; biomarkör; Medicinsk vetenskap; Medical Science;

    Sammanfattning : This thesis investigated the efficacy and safety of autologous hematopoietic stem cell transplantation (AHSCT) as a treatment of multiple sclerosis. This thesis demonstrates that when compared to one of the most powerful disease-modifying drugs (DMDs), specifically alemtuzumab (ALZ), AHSCT is able to hold its ground. LÄS MER

  4. 3. Studies of the Biology of Intrathecal Treatment in Progressive MS

    Författare :Joakim Bergman; Anders Svenningsson; A. Tommy Bergenheim; Jonathan D. Gilthorpe; Joachim Burman; Magnus Andersson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Progressive Multiple Sclerosis; intrathecal treatment; Ommaya reservoir; anti-CD20 therapy; microdialysis; cerebrospinal fluid; CNS compartments; Progressiv Multipel Skleros; intratekal behandling; Ommaya reservoar; anti-CD20 terapi; mikrodialys; ryggmärgsvätska; sektioner i centrala nervsystemet; Neurology; neurologi;

    Sammanfattning : Background: Multiple Sclerosis (MS) is a chronic, inflammatory, autoimmune disease, affecting the central nervous system (CNS). About 85% of afflicted present with a relapsing-remitting form of the disease (RRMS), for which a breakthrough in treatment was made in 2008 with rituximab, an antibody directed towards CD20, a surface antigen on B-cells. LÄS MER

  5. 4. Omic Network Modules in Complex diseases

    Författare :Tejaswi Venkata Satya Badam; Mika Gustafsson; Zelmina Lubovac-Pilav; Maja Jagodic; Sergio Baranzini; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Biological systems encompass various molecular entities such as genes, proteins, and other biological molecules, including interactions among those components. Understanding a given phenotype, the functioning of a cell or tissue, aetiology of disease, or cellular organization, requires accurate measurements of the abundance profiles of these molecular entities in the form of biomedical data. LÄS MER

  7. 5. Women on sick leave for long-term musculoskeletal pain : Factors associated with work ability, well-being and return to work

    Författare :Mamunur Rashid; Annika Nilsson; Marja-Leena Kristofferzon; Marina Heiden; Katja Boersma; Högskolan i Gävle; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biopsychosocial model; musculoskeletal pain; postal survey; prognostic factors; return to work; sick leave; women of working age; work ability and well-being; inget Strategiskt forskningsområde SFO ; no Strategic Research Area SFO ;

    Sammanfattning : Background: Taking sick leave (SL) for long-term musculoskeletal pain (MSP), predominantly in the neck, shoulders and back, is common among women in Sweden. Long-term MSP affects their daily life and causes impaired work ability and long-term SL. LÄS MER