Sökning: "multifactorial explanation"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden multifactorial explanation.

  1. 1. Om det som är - ontologins metodologiska relevans inom positivism, relativism och kritisk realism : Concerning Being. Ontology and its methodological relevance within Positivism, Relativism and Critical Realism

    Författare :Daniel Seldén; Göteborgs universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; ontology; methodology; critical realism; positivism; relativism; anorexia nervosa; sociology; multifactorial explanation; biopsychosocial;

    Sammanfattning : The main puq)ose of this thesis is to argue for the methodolo~.,'ical rclevance of a critical realist, stratified ontology for the process of scientific knowledge production. The case of anorexia nervosa is ch osen to illustrate thc argumcnt. LÄS MER

  3. 2. Ultrasound and atherosclerosis. Evaluation of methods, risk factors and intervention

    Författare :Jerker Persson; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical physics; Kardiovaskulära systemet; Cardiovascular system; validation; ultrasound; reproducibility; progression; plaque; intima-media thickness; intervention; atherosclerosis; epidemiology; cardiovascular risk factors; radiology; tomography; medical instrumentation; Klinisk fysiologi; radiologi; tomografi; medicinsk instrumentering;

    Sammanfattning : The importance of studying cardiovascular disease before the process leads to hard end-points has been recognised, and methods to quantify early atherosclerosis have been taken in use in many research centres around the world. An ultrasound method with a computer assisted image analysing system was developed in co-operation with the Wallenberg Laboratory for Cardiovascular Research and Chalmers University of Technology in Gothenburg, Sweden. LÄS MER

  4. 3. The influence of opioids on gastric function : experimental and clinical studies

    Författare :Jakob Walldén; Magnus Wattwil; Sven-Egron Thörn; Eldar Søreide; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gastrointestinal motility; gastric emptying; gastric tone; electrogastrography; analgesics; opioids; µ-opioid receptor; polymorphism; Surgery; Kirurgi; Surgery; Kirurgi;

    Sammanfattning : Efter operation och anestesi får patienter ofta en negativ påverkan på magsäck och tarmar. Illamående och kräkningar är ett stort problem och många har svårt att komma igång med intag av föda och normal tarmfunktion då magsäcken och tarmarna ”står stilla”. Flera faktorer bidrar- bl.a. LÄS MER

  5. 4. Crosstalk between colorectal cancer cells and tumour-associated macrophages

    Författare :Yuan Zhang; Malmö Cellpatologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CD47; tumour-associated macrophage; matrix metalloproteinase; cell migration; colon cancer;

    Sammanfattning : Colorectal cancer (CRC) is the third most common cancer and the fourth leading cause of death from cancer worldwide. People suffering from inflammatory bowel disease, such as Crohns’ disease and ulcerative colitis, are at an increased risk of developing CRC. The development of CRC is highly influenced by the tumour microenvironment. LÄS MER

  7. 5. Mechanisms by which variants in the TCF7L2 gene increase the risk of developing Type 2 diabetes

    Författare :Yuedan Zhou; diabetes och endokrinologi Genomik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TCF7L2; rs7903146; Type 2 diabetes; β cell function; β cell survival; insulin secretion; proinsulin synthesis; proinsulin-to-insulin conversion; insulin maturation; open chromain; exon skipping; p53; TP53INP1; ISL1; MAFA; NEUROD1; PDX1; NKX6.1; PCSK1; PCSK2; SLC30A8; GWAS.;

    Sammanfattning : Type 2 diabetes mellitus (T2DM) is a heterogeneous disease with a multifactorial aetiology comprising of genetic and environmental factors. The common variant most highly associated with T2DM known to date is a SNP rs7903146 in the TCF7L2 gene. However, the role TCF7L2 plays in the development of T2DM was unclear. LÄS MER