Sökning: "multi-generation"
Visar resultat 21 - 25 av 36 avhandlingar innehållade ordet multi-generation.
21. Localization of five human genes by clinical and molecular genetic methods
Sammanfattning : Four of the research projects reported in this thesis start from the gene effects observed in clinical practice. Finding a disease causing gene is challenging, exciting and beneficial for the patient, the family and for the society. LÄS MER
22. Health consequences of adverse fetal growth : studies in twins
Sammanfattning : Findings of associations between birth weight and adult health outcomes have been taken to indicate that fetal growth – and fetal nutrition in particular – may program future health and disease in the developing individual. However, the study of prenatal exposures in humans is challenging, and most of the evidence to support fetal programming thus rests on proxy measures, such as birth weight and birth weight for gestational age. LÄS MER
23. Familial Risks of Heart Failure in Sweden
Sammanfattning : Introduction: Despite major advances, the incidence rate and mortality of heart failure (HF) remains high, with a five-year survival of approximately 50%. At the time of inception of this thesis the familial risks of HF, including the aspects of mortality, were largely underdetermined. LÄS MER
24. Cancer risks and prognosis in familial melanoma kindreds
Sammanfattning : Malignant melanoma of the skin is one of the most rapidly increasing cancers in many western countries, including Sweden. This incidence rise is mainly attributed to sun-seeking habits with increased intermittent UVR exposure, a major risk factor for melanoma. LÄS MER
25. The risk of malignancy in women with endometriosis
Sammanfattning : The aim of this thesis was to investigate the association between endometriosis and malignancies also after controlling for parity, to investigate the impact of endometriosis on survival after a malignancy diagnosis and to investigate the association between treatment of endometriosis and ovarian cancer risk. In a population based cohort study on the association between endometriosis and malignancy, 64 492 women with a first time discharge diagnosis of endometriosis between 1969 and 2000, were included and 3 349 incident cases of a malignancy recorded. LÄS MER