Sökning: "multi-domain enzyme"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden multi-domain enzyme.

  1. 1. Feruloyl esterases - Evaluation of their potential for biotechnological applications

    Författare :Cyrielle Bonzom; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; multi-domain enzyme; acetyl esterase; enzyme immobilization; N-glycosylation; carbohydrate active enzyme family 1; acetyl xylan esterase; heterologous production; polysaccharide utilization loci; enzyme stability; feruloyl esterase;

    Sammanfattning : Owing to the current efforts to find sustainable alternatives to petrochemical based industries and technologies, enzymatic degradation and valorization of plant biomass has been attracting interest. Due to the complexity of plant biomass, an array of enzymes is required to hydrolyze it, including esterases. LÄS MER

  3. 2. Production and investigation of highly thermophilic multi-domain carbohydrate-active enzymes

    Författare :Daniel Krska; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; protein structure; xylanase; carbohydrate esterase; multidomain enzymes; carbohydrate-active enzymes; thermostable enzymes; plant biomass degradation; Caldicellulosiruptor;

    Sammanfattning : With the looming threat of climate change caused largely by an excess of carbon dioxide in the atmosphere, recent scientific efforts have focused on the substitution of fossil fuels and other polluting compounds with more environmentally conscious choices. To this end, the investigation of biomass as both a renewable source of energy and as a chemical basis to produce high-value products is being extensively investigated. LÄS MER

  4. 3. Mechanistic insights into the biosynthesis of polyketide antibiotics

    Författare :Azmiri Sultana; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Anthracyclines are a group of aromatic polyketide compounds with significant medical importance due to their antineoplastic properties. Doxorubicin and daunorubicin members of this family are among the two most commonly used anticancer drugs. However, these compounds exhibit severe side effects like cardiotoxicity and multi-drug resistance. LÄS MER

  5. 4. Functional studies of Escherichia coli stringent response factor RelA

    Författare :Ievgen Dzhygyr; Vasili Hauryliuk; Jörgen Johansson; Greg Bokinsky; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Stringent response; RelA; p ppGpp; ribosome; tRNA; metabolism regulation; allosteric regulation; translation; nutritional stress; molekylärbiologi; Molecular Biology;

    Sammanfattning : RelA is a ribosome associated multi-domain enzyme, which plays a crucial role in adaptation ofEscherichia coli to nutritional stress as such as amino acid deficiency. It detects the deficiency of aminoacids in the cell by monitoring whether a tRNA at the acceptor site (A-site) of the ribosome is chargedwith amino acid or not. LÄS MER

  7. 5. Bioinformatics, evolution and revolution in our understanding of toxin-antitoxin systems

    Författare :Chayan Kumar Saha; Gemma C. Atkinson; Victoria Shingler; Gipsi Lima Mendez; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Bioinformatics; Alarmones; Evolution; Gene neighbourhood; Toxin; Antitoxin; molekylärbiologi; Molecular Biology;

    Sammanfattning : Bacteria experience a wide range of natural challenges during their life cycles, to which they must respond and adapt to live. Under stressed conditions such as amino acid starvation, bacteria slow down their growth mechanism by producing small alarmone nucleotides guanosine pentaphosphate (pppGpp) and tetraphosphate (ppGpp), collectively referred to as (p)ppGpp. LÄS MER