Sökning: "mucosal injury"

Visar resultat 11 - 15 av 27 avhandlingar innehållade orden mucosal injury.

1. 11. Splanchnic perfusion in cardiac surgery

   Författare :Anders Thorén; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Splanchnic circulation; jejunal mucosal perfusion; laser Doppler flowmetry; cardiopulmonary bypass; cardiac surgery; inotropic agents; gastric tonometry; sympathetic reflex;

   Sammanfattning : Splanchnic ischemia in cardiac surgery is considered a risk factor in the development of the Multiple Organ Dysfunction Syndrome (MODS), which is the leading cause of morbidity and mortality in the intensive care unit. Splanchnic ischemia/reperfusion may lead to an injury of the intestinal mucosa and induce a systemic inflammation (SIRS), which is proposed to precede MODS. LÄS MER

3. 12. On intestinal ischaemia after aortoiliac surgery : Epidemiological, clinical and experimental studies

   Författare :Martin Björck; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Ischaemia; intestines; colon; ischaemic colitis; aorta-abdominal; aortic aneurysm-abdominal; aortic rupture; atherosclerosis; postoperative complications; cohort studies; case-control studies; clinical protocols; experimental design; incidence; risk factors; diagnosis; treatment outcome; intra-mucosal pH; pHi; swine; splanchnic circulation; haemodynamics; dobutamine; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

   Sammanfattning : An important cause of death among patients undergoing surgery of the abdominal aorta is intestinal ischaemia. In the Swedish Vascular Registry 2930 aortoiliac operations were identified. The complication was studied in a combined cohort and case-control study, and multivariate analysis performed. The incidence of intestinal ischaemia was 2. LÄS MER

4. 13. Role of Melatonin, Neuropeptide S and Short Chain Fatty Acids in Regulation of Duodenal Mucosal Barrier Function and Motility

   Författare :Wan Salman Wan Saudi; Markus Sjöblom; Olof Nylander; Mark Berner-Hansen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 51Cr-EDTA; rat; in vivo; duodenum; enteric nervous system; paralytic ileus; parecoxib; bicarbonate secretion; motility; ethanol; HCl; melatonin; neuropeptide S; short chain fatty acids; chemosensing; Physiology; Fysiologi;

   Sammanfattning : The duodenal epithelium is regularly exposed to HCl, digestive enzymes, bacteria and toxins, and sometimes also to ethanol and drugs. The imbalance of aggressive factors in the intestinal lumen and mucosal barrier function increases the risk of tissue injury and inflammation. LÄS MER

5. 14. Attenuation of Oxidative Stress, Inflammation and Colorectal Oncogenesis by Food Constituents: Ischaemia/Reperfusion Injury and Induced Colitis in Rodents

   Författare :Åsa Håkansson; Avdelningen för livsmedel och läkemedel; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; Ischaemia Reperfusion; Rose hips; Colitis; Probiotics; Inflammation; Blueberry;

   Sammanfattning : The enteric microbiota is increasingly implicated as a central factor in the development of intestinal inflammation in humans and experimental animals, and the intestinal environment is considered important in both colorectal cancer development and modulation of mucosal immunity. Diet-induced changes in the different populations of the intestinal microbiota can be achieved by use of probiotic bacteria, dietary fibre and berries rich in phenolic compounds. LÄS MER

7. 15. Splanchnic organ homeostasis in experimental endotoxin shock : with special reference to the endothelin and renin-angiotensin systems

   Författare :Anders Oldner; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Endotoxin; endothelin; angiotensin II shock; tonometry microdialysis; porcine; hypoxanthine; gut; splanchnic circulation; lactate; mucosal pHi;

   Sammanfattning : Splanchnic organ homeostasis may become severely deteriorated in states of sepsis and endotoxaemia. Gut tissue hypoxia with subsequent increases in intestinal mucosal permeability has been proposed to contribute to the development of multiple organ failure. LÄS MER