Sökning: "mucin 1"

Visar resultat 1 - 5 av 55 avhandlingar innehållade orden mucin 1.

  1. 1. Tumor biological aspects of the mucin-like glycoprotein CD43

    Författare :Sirle Laos; Göteborgs universitet; []
    Nyckelord :CD43; leukosialin; sialophorin; mucin; colon adenoma; proteolytic processing; ; NF-kappaB; p65; chemokine; p53; ARF; Fas; apoptosis; transformation;

    Sammanfattning : Cancer cells overexpress aberrant forms and amounts of mucins, which contribute to tumor development by regulating cell growth, survival, adhesion, invasion and immune responses. CD43, a type I transmembrane protein, is a mucin-like molecule expressed under normal physiological conditions by most hematopoietic cell types. LÄS MER

  3. 2. Molecular associations and transport properties of amphiphiles and gastrointestinal mucin in aqueous solution

    Författare :Géraldine Lafitte; Fysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Fysikalisk kemi; transport properties; diffusion NMR; Magnetic resonance imaging; Physical chemistry; hydrophobic association; electrostatic repulsion; gel; Mucin; Surfactant;

    Sammanfattning : An effective uptake/absorption of drug formulations involve many processes; one being the transport of the active molecule through the mucus layer. The mucus layer is a complex mixture of biological molecules. Among them, mucin is the molecule that mainly provides the gel properties of the layer. LÄS MER

  4. 3. Interactions of Mucins with Biopolymers and Drug Delivery Particles

    Författare :Olof Svensson; Malmö högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mucin; chitosan; lactoperoxidase; multilayer; mucoadhesion; nanoparticles; ellipsometry;

    Sammanfattning : The main components in the mucous gels apart from water are mucins, which are proteins with high molecular weights and an abundance of negatively charged oligosaccharide side chains. The aim of the investigations was to characterize interactions between mucins and other proteins that are present in the mucous gel, and also between mucins and components used in pharmaceutical formulations. LÄS MER

  5. 4. Adsorption of biopolymers and their layer-by-layer assemblies on hydrophilic surfaces

    Författare :Maria Lundin; Eva Blomberg; Thomas Arnebrant; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Layer-by-layer; multilayer; adsorption; biopolymers; Chitosan; Heparin; Mucin; Albumin; Lysozyme; β-casein; SDS; QCM-D; Ellipsometri; DPI; TIRF; FRET; SFA; layer structure; solvent content; vertical diffusion; exponential growth; solid-liquid interface; deposition conditions; Surface and colloid chemistry; Yt- och kolloidkemi;

    Sammanfattning : It is widely known that surfaces play an important role in numerous biological processes and technological applications. Thus, being able to modify surface properties provides an opportunity to control many phenomena occurring at interfaces. LÄS MER

  7. 5. Study of the colonic mucus layer by mass spectrometry

    Författare :Sjoerd van der Post; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MUC2; mucin; intestine; proteomics; mass spectrometry;

    Sammanfattning : The mucus covering our internal mucosal surfaces is a part of the innate immune system, and the first line of defense against microbial challenges. The need of an efficient defense system is especially important in the lower parts of the digestive tract where the microbiota reaches its highest density. LÄS MER