Sökning: "motoneuron"

Visar resultat 16 - 20 av 27 avhandlingar innehållade ordet motoneuron.

  1. 16. Immune recognition molecules in synaptic plasticity and regeneration of spinal motoneurons

    Författare :Sebastian Thams; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This thesis is based on the emerging concept that pattern recognition molecules, originally characterized in the immune system, may be expressed and used by neurons to mediate non-immune functions. In line with this concept, the major histocompatibility complex (MHC) class I and certain complements proteins have been implicated in synaptic plasticity in the developing visual system. LÄS MER

  3. 17. Motor control in zebrafish : excitatory drive and developmental changes

    Författare :Sabine Görgens; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : An essential characteristic of human and animal life is the ability to move from one place to another, in order to survive in a complex environment. All the different forms of locomotion, like walking, swimming, crawling and flying, have one common feature: rhythmic and alternating movements of the body. LÄS MER

  4. 18. Purine and Pyrazolopyrimidine Derivatives: Design and Synthesis of Chemical Tools for Biological Applications

    Författare :David Bliman; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; purine; pyrazolopyrimidine; caged compounds; protein kinases; protein-protein interactions; fluorescence; organic synthesis;

    Sammanfattning : Purines can be found in a multitude of naturally occurring compounds with a range of functions. This thesis describes the design and synthesis of purines and structurally related pyrazolopyrimidine derivatives intended for biological applications. LÄS MER

  5. 19. On the cholinergic c-bouton

    Författare :Johan Hellström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Acetylcholine; Brainstem; Immunohistochemistry; In situ hybridization; Motoneurons; Muscarinic receptors; Rat; Spinal cord; Ventral horn cells;

    Sammanfattning : The cholinergic C-bouton is a large nerve terminal type exclusively contacting motoneuron cell somata and proximal dendrites. C-boutons are characterized by subsurface cisterns found beneath the postsynaptic membrane, which is an exclusive feature for these nerve terminals. The origin of the C-boutons is unknown. LÄS MER

  7. 20. Anti-Apoptotic Proteins in Nerve Cell Survival and Neurodegeneration

    Författare :Laura Korhonen; Marja Jäättelä; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; neuronal cell death; XIAP; RIAP-2; Hippocalcin; Bcl-2; Bcl-X; kainic acid; DRG; estrogen; Neurovetenskap; Neurology; Neurologi; Developmental Neurosciences; medicinsk utvecklings- och neurobiologi;

    Sammanfattning : Apoptosis is a genetically regulated cell death program, which shows distinct morphological characteristics. It takes place during neuronal development and in some neurodegenerative diseases. During apoptosis, the intracellular proteins are degraded by various caspases, cysteine aspartases, which are regulated by pro- and anti-apoptotic signals. LÄS MER