Sökning: "moritz lübke"

Hittade 1 avhandling innehållade orden moritz lübke.

1. 1. Deciphering ret signalling in cell biology and development

   Författare :Moritz Lübke; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The rearranged during transformation (RET) tyrosine kinase regulates a plethora of biological processes such as cell survival, proliferation and migration and is essential for the normal development of several organs such as the sensory, enteric and sympathetic nervous systems and the kidneys. After RET activation by its ligands several intracellular tyrosine residues are phosphorylated and serve as binding sites for adaptor proteins that activate different downstream signalling pathways. LÄS MER