Sökning: "montelukast"

Visar resultat 1 - 5 av 8 avhandlingar innehållade ordet montelukast.

  1. 1. Functional Aspects of Epithelia in Cystic Fibrosis and Asthma

    Författare :Zhanna Servetnyk; Godfried Roomans; Michael Wilschansky; Uppsala universitet; []
    Nyckelord :Cell biology; cystic fibrosis; CFTR; chloride transport; airway epithelium; sweat gland; asthma; corticosteroids; montelukast; Cellbiologi;

    Sammanfattning : The cystic fibrosis transmembrane conductance regulator (CFTR), a cAMP activated chloride channel in the apical membrane of epithelial cells, is defective in patients with cystic fibrosis (CF). Research efforts are focused on chloride channel function in order to find a cure for the disease. LÄS MER

  3. 2. Modulation of cytokine production by mononuclear cells in allergic inflammation. The effects of allergen exposure and anti-inflammatory agents

    Författare :Katarzyna Wosinska-Becler; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cytokines; seasonal allergy; kinetics; CysLTR1 antagonist; montelukast; rush immunotherapy; monocyte; basophil; eosinophil; NK cell; T cell;

    Sammanfattning : In pollen-sensitized subjects, seasonal allergen exposure results in clinical allergic disease, which in affected tissues displays a morphological picture typical of chronic inflammation. The cellular responses to allergens include the production of inflammatory cytokines that can be examined in peripheral blood cells. LÄS MER

  4. 3. Ultrastructural Studies of the Airway Epithelium in Airway Diseases

    Författare :Eyman Shebani; Godfried M. Roomans; Marie Johannesson; Anil Mehta; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Morphology; asthma; cilia; corticosteroids; cytokines; desmosomes; Gaucher’s disease; montelukast; primary ciliary dyskinesia; transmission electron microscopy; Morfologi; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi;

    Sammanfattning : Ultrastructural studies of airway epithelium in airway disease are important for diagnosis and understanding the underlying pathology which helps clinicians to improve the patients' treatment.Airway biopsies from a 5-month old boy with respiratory problems and gastro-oesophageal reflux were studied by transmission electron microscopy (TEM). LÄS MER

  5. 4. The Role of Inflammatory Lipid Mediators on Colon Cancer Initiating Cells (CICs)

    Författare :Kishan Bellamkonda; Malmö Cellpatologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Colorectal cancer (CRC) is one of the major causes of cancer globally. Recent studies proposed a role for cancer initiating cells (CICs), a small subset of replication-competent cells, in colon carcinogenesis. LÄS MER

  7. 5. Extracellular vesicles : mediators of immune modulation in the lung and as therapeutic vehicles

    Författare :Casper Ullsten-Wahlund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Extracellular vesicles (EVs) are released from all cell types, and carry a wide setup of proteins, nucleic acids, lipids and other cargo. The overall aim of this thesis is to explore EV-based immune therapy, but also to find clues on mechanisms of the inflammatory disease sarcoidosis, and of lung cancer. LÄS MER