Sökning: "monozygotic"
Visar resultat 1 - 5 av 64 avhandlingar innehållade ordet monozygotic.
1. Post-zygotic Genetic Variation in Health and Disease
Sammanfattning : Post-zygotic genetic variation has previously been shown in healthy individuals and linked to various disorders. The definition of post-zygotic or somatic variation is the existence of genetically distinct populations of cells in a subject derived from a single zygote. LÄS MER
2. Complement-mediated kidney diseases: Genotype, phenotype and inhibition studies
Sammanfattning : Complement-mediated kidney diseases are ultrarare conditions characterized by excess complement activation related in most cases to complement gene variants or circulating autoantibodies. These conditions are chronic and can lead to kidney failure. LÄS MER
3. Defense-related inhibition of sympathetic nerve activity: Insights from neuroimaging and monozygotic twins on related cortical processes and clinical potential
Sammanfattning : This thesis investigates a physiological phenomenon observed in the peripheral sympathetic nervous system in response to various stressors and tries to bring it closer to clinical research. Sudden surprising stimulation can evoke a transient inhibition of sympathetic nerve activity to blood vessels in the human body which is also predictive of the blood pressure response. LÄS MER
4. Genetic and environmental aspects of symptomatic gallstone disease
Sammanfattning : Gallstone disease (GD) represents a major healthcare problem. Gallstones are likely to result from a complex interaction of the environment and the effects of multiple undetermined genes. LÄS MER
5. Inflammatory bowel disease in twins : studies of genetics and environmental factors
Sammanfattning : The aetiology of inflammatory bowel disease (IBD) is unknown but considered to be caused by interplay of genetic and environmental factors.The aims of this thesis were to study the influence of genetics and environmental factors in aetiology, disease phenotype and levels of Anti-Saccharomyces cerevisiae antibodies (ASCA), as well as to assess whether CARD15/NOD2 polymorphisms explain the influence of genetics in these aspects. LÄS MER