Sökning: "monolithic bed"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden monolithic bed.

  1. 1. CALIBRATION OF CHROMATOGRAPHY MODELS

    Författare :Patrik Persson; Avdelningen för kemiteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; film mass transfer resistance; Kemiteknik och kemisk teknologi; sorption kinetics; external volume; monolithic bed; shallow bed; packed bed; capillary model; detailed model; computer simulation; parameter estimation; diffusion; model calibration; Chromatography; modelling; proteins; Chemical technology and engineering;

    Sammanfattning : AbstractThis thesis is devoted to calibration of mathematical chromatography models. Chromatography models include unknown parameters that must be determined before the models can be applied to optimization or scale-up of a chromatography process. LÄS MER

  3. 2. Protein Recovery Using Simulated Moving Bed Technology and Macroporous Chromatographic Support Material

    Författare :Jonatan Andersson; Bioteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Bioteknik; Biotechnology; Chromatography; Simulated Moving Bed; Protein;

    Sammanfattning : Due to its gentle and high resolving power, chromatography is the work horse within protein separation. Still it is an expensive method due to low productivity, diluted product streams, large waste streams and expensive support material. This limits its potential use to areas of high price products. LÄS MER

  4. 3. Primary Recovery of Biologically Active Compounds Using Macroporous Monolithic Hydrogels

    Författare :Amro Hanora; Bioteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Downstream processing; macroporous; Biologically active compounds; Biotechnology; Läkemedelsteknik och relaterad teknik; Pharmaceutical and related technologies; Polymerteknik; biopolymers; Biokemisk teknik; Polymer technology; Makromolekylär kemi; Biochemical technology; Affinity chromatography; Ion exchange chromatography; Expanded bed adsorption chromatography.; Macromolecular chemistry; High through put screening; lactica acids; Endotoxin; Plasmid DNA; Cryogel columns; Bioteknik;

    Sammanfattning : The completion of sequencing of human and other mammalian genomes opens a new era for drug development. New approaches have been proposed for tackling diseases such as development of small molecule therapies based on understanding of human genome and proteome, new proteinous based therapies, where the therapeutic protein can inhibit or modify a certain metabolic pathway or DNA-based therapies delivering a gene into the cell (e. LÄS MER

  5. 4. Fast isolation of proteins from bioreactors using affinity chromatography techniques

    Författare :Eva Pålsson; Avdelningen för klinisk genetik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; chromatography; protein purification; analyses; dispersion; chromatography matrices; Biochemistry; Biokemi; Metabolism; expanded bed; metabolism; Biotechnology; Bioteknik;

    Sammanfattning : The purification of proteins from raw materials like fermentation broth and other biological sources usually involves several purification steps and is rather time consuming and expensive. This is a major concern in the production of many important protein products e.g. pharmaceuticals such as insulin and blood coagulation factors. LÄS MER

  7. 5. New Techniques for Sample Preparation in Analytical Chemistry : Microextraction in Packed Syringe (MEPS) and Methacrylate Based Monolithic Pipette Tips

    Författare :Zeki Altun; Lars G Blomberg; Stig Pedersen-Bjergaard; Karlstads universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Liquid Chromatography Tandem Mass Spectrometry; Local Anaesthetics; Microextraction in Packed Syringe; Monoliths; Pipette Tips; Sample Preparation; Analytical chemistry; Analytisk kemi; Kemi; Chemistry;

    Sammanfattning : Sample preparation is often a bottleneck in systems for chemical analysis. The aim of this work was to investigate and develop new techniques to address some of the shortcomings of current sample preparation methods. LÄS MER