Sökning: "monocytes macrophages"

Visar resultat 6 - 10 av 144 avhandlingar innehållade orden monocytes macrophages.

  1. 6. Macrophage programming and host responses to bacterial infection

    Författare :Xiao Wang; Hong Sjölinder; Martin Rottenberg; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Macrophages; meningococci; mycobacteria; NhhA; CD46; cytokines; molekylärgenetik; Molecular Genetics;

    Sammanfattning : Macrophages are dynamic, plastic, and heterogeneous immune cells that play an important role in host immune defense against bacterial infection. Various bacterial pathogens, such as Neisseria meningitidis and Mycobacterium tuberculosis, can modulate host immune responses by interfering with macrophage differentiation and polarization. LÄS MER

  3. 7. Novel actions of thrombin-derived host defense peptides

    Författare :Finja Hansen; Lund Dermatologi och venereologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Host defense peptides; Thrombin; Monocytes Macrophages; Gram-negative bacteria; LPS; TLR; Phagocytosis; Inflammation; Endocytosis;

    Sammanfattning : Thrombin-derived C-terminal peptides (TCPs) constitute a novel class of immunomodulatory host defense peptides, generated during infection and inflammation. Previous investigations have shown that TCPs of 2-3 kDa inhibit pro-inflammatory immune responses in vitro and in vivo, but their mode of action remained unclear. LÄS MER

  4. 8. Local Immune regulation in human pregnancy : with focus on decidual macrophages

    Författare :Charlotte Gustafsson Lidström; Christina Ekerfelt; Eva Sverremark-Ekström; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reproduction; placenta; leukocyte; ELISPOT; Clinical immunology; Klinisk immunologi;

    Sammanfattning : During pregnancy, the woman carries a fetus partly foreign to her immune system, because of the expression of paternal antigens. Despite this, the fetus is normally tolerated and not rejected, as is often the case with organs in allogeneic transplantations. LÄS MER

  5. 9. On the regulation and effects of chronic inflammation in inflammatory bowel disease

    Författare :Olof Grip; Gastroenterologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gastroenterologi; statins; monocytes; eosinophils; dysplasia; thrombosis; ulcerative colitis; Crohn s disease; inflammation; inflammatory bowel disease; Gastro-enterology;

    Sammanfattning : Inflammatory bowel disease is thought to result from the inappropriate and ongoing activation of the mucosal immune system driven by the presence of normal luminal flora. In this process monocytes/macrophages contribute to and maintain chronic inflammation by being both regulatory and effector cells. LÄS MER

  7. 10. Macrophage expression of VEGF and VEGFR-1. Potential involvement in atherogenesis

    Författare :Linda Salomonsson; Göteborgs universitet; []
    Nyckelord :atherosclerosis; macrophages; oxLDL; statins; VEGF; VEGFR-1;

    Sammanfattning : The vascular endothelial growth factor (VEGF) family is a group of proteins which contributes to both neovascularisation and inflammation. Elevated levels of VEGF have been found in subjects with atherosclerosis and correlate to several cardiovascular risk factors, e.g. hypertension and hyperlipidemia. LÄS MER