Sökning: "monocytes macrophages"

Visar resultat 21 - 25 av 144 avhandlingar innehållade orden monocytes macrophages.

  1. 21. Exploring mechanisms regulating the heterogeneity of tumor-associated macrophages

    Författare :Majken Wallerius; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Accumulation of macrophages in the tumor microenvironment is associated to poor prognoses in most human cancers. Tumor-associated macrophages (TAMs) represent a heterogeneous and plastic population of cells that contribute to tumor growth, metastatic dissemination, angiogenesis, and immune suppression. LÄS MER

  3. 22. Immune modulation of macrophages by the meningococcal surface protein NhhA

    Författare :Xiao Wang; Hong Sjölinder; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Functional immune modulation of macrophages play important role during bacterial infection. Neisseria meningitidis, a gram-negative diplococcal bacterium, is the leading cause of bacterial meningitis and fatal septic shock. However, it is also a commensal bacterium that colonizes the nasopharynx of healthy individuals asymptomatically. LÄS MER

  4. 23. Eicosanoids and exosomes : a link between macrophages and lung cancer

    Författare :Ana Lukic; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic inflammation increases the risk of lung cancer. Macrophages (MO) are important players in inflammation, with regulatory and executive functions. Eicosanoids and exosomes can be both triggers and mediators of these functions. LÄS MER

  5. 24. Inflammatory cell death of human macrophages induced by Aggregatibacter actinomycetemcomitans leukotoxin

    Författare :Peyman Kelk; Anders Johansson; Charels A Dinarello; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aggregatibacter actinomycetemcomitans; leukotoxin; IL-1β; caspase-1; inflammatory cell death; pyroptosis; ODONTOLOGY; ODONTOLOGI; odontologi; Odontology;

    Sammanfattning : Aggregatibacter (Actinobacillus) actinomycetemcomitans is a bacterium mainly associated with aggressive forms of periodontitis. Among its virulence factors, a leukotoxin is suggested to play an important role in the pathogenicity. LÄS MER

  7. 25. Expression profiling of human macrophages and atherosclerotic plaques to identify genes and mechanisms that modulate the development of atherosclerosis

    Författare :Daniel Hägg; Göteborgs universitet; []
    Nyckelord :;

    Sammanfattning : Macrophages play an important role in atherosclerosis, a disease that affects large and medium size arteries and causes clinical manifestations such as myocardial infarction or stroke. The aim of this thesis was to identify genes that are important in the development of atherosclerosis. LÄS MER