Sökning: "monoaminergic"
Visar resultat 1 - 5 av 43 avhandlingar innehållade ordet monoaminergic.
1. Anabolic androgenic steroids and central monoaminergic systems : Supratherapeutic doses of nandrolone decanoate affect dopamine and serotonin
Sammanfattning : Supratherapeutic doses of anabolic androgenic steroids (AASs) are administered, not only as performance-enhancing drugs in the world of sports, but also in order to modify behaviour. AAS abusers are at risk of developing serious physical and psychological side effects such as dependence and aggressive behaviour. LÄS MER
2. PET studies on the mechanism of monoaminergic drugs
Sammanfattning : Positron emission tomography (PET) is a molecular imaging technique that allows for examinations of neurochemistry directly in the living human brain. In the present thesis, PET was used to assess the pharmacological effects of two drugs representing the major classes of antipsychotic and antidepressant drugs. LÄS MER
3. Monoaminergic modulation in spinal reflex pathways from group I afferents
Sammanfattning : Serotonin and noradrenaline are known to play an important part in modulation of spinal neuronal networks. Group I muscle afferents mediate information on dynamic changes of muscle length and tension, and modulation of actions from these afferents could be of importance for the execution of movements. LÄS MER
4. Pharmacological control of ciliary activity in the young sea urchin larva : cholinergic and monoaminergic effects and the role of calcium and cyclic nucleotides
Sammanfattning : The ciliary activity of the young (prenervous) sea urchin larva, reflected by its swimming intensity, is measured according to a simple method. The changes in ciliary activity from hatching throughout gastrulation commonly show two main peaks coinciding with the two main phases of gastrulation. LÄS MER
5. Regulation of monoaminergic functions by GPCRs with a special emphasis on mental and movement disorders
Sammanfattning : Dysfunction of the brain’s monoaminergic system has been implicated in many human neurological and psychiatric disorders, such as Parkinson’s disease (PD), major depressive disorder (MDD) and schizophrenia. The monoamines that are most dysregulated in these diseases, are dopamine and serotonin. LÄS MER