Sökning: "monitoring therapy effect"

Visar resultat 11 - 15 av 75 avhandlingar innehållade orden monitoring therapy effect.

  1. 11. Mechanistic study of antiangiogenic agents in cancer therapy

    Författare :Yin Zhang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Tumor growth and metastasis are dependent on angiogenesis that constantly alters the tumor microenvironment. Based on the antiangiogenic principle proposed more than 40 years ago by Dr. LÄS MER

  3. 12. DNA analogs for the purpose of gene therapy

    Författare :Mathias G Svahn; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This thesis describes DNA analogs and their potential use for gene therapeutic purposes, primarily by sequence specific strand-invasion of double-stranded DNA. Gene therapy is classically thought of as restoration of a defect gene. LÄS MER

  4. 13. Metastatic Breast Cancer: Biomolecular Characterization and Targeted Therapy

    Författare :Siker Kimbung; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Metastatic breast cancer; biomarker conversion; liver metastasis-selective genes; prognosis; BRCA1; PARP1;

    Sammanfattning : Metastasis is a complex process that remains a major challenge in the clinical management of cancer, because most cancer-related deaths are attributed to disseminated disease rather than the primary tumor. Despite the significant advances in the prediction of prognosis, and therapeutic management of primary breast cancers, coupled with the substantial improvement in our understanding of the molecular determinants of metastasis, breast cancer relapse and death rates remain unacceptably high. LÄS MER

  5. 14. Inflammatory markers for evaluation of inflammatory bowel disease therapy

    Författare :Maria Lönnkvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The lack of reliable biomarkers for predicting the clinical course or monitoring therapeutic outcome in inflammatory bowel disease is an indisputable problem. The aim of this study was to evaluate markers of inflammation during inflammatory bowel disease therapy. LÄS MER

  7. 15. Self-monitoring av intraocular pressure and its clinical application

    Författare :Laurence Quérat; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Purpose: Measuring the intraocular pressure (IOP) is one of the most common ophthalmologic examinations, especially within glaucoma management. An elevated IOP is a major risk factor for the development and progression of glaucoma, and is so far the only modifiable parameter. LÄS MER