Sökning: "molekylärgenetiska studier av"

Visar resultat 1 - 5 av 13 avhandlingar innehållade orden molekylärgenetiska studier av.

  1. 1. Molecular Genetic Studies of Genes Predisposing for Glaucoma

    Författare :Mattias Jansson; Claes Wadelius; Annika Lindblom; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; glaucoma; MYOC; OCLM; GSTM1; OPTN; mutation analysis; Genetik; Clinical genetics; Klinisk genetik;

    Sammanfattning : Glaucoma is one of the leading causes of visual impairment in the world. In glaucoma, the patient’s peripheral vision is lost due to progressive and irreversible deterioration of the retinal ganglion cells and atrophy of the optic nerve. LÄS MER

  3. 2. Molecular Genetic Alterations In Endometrial And Ovarian Cancers

    Författare :Anjila Koul; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; KRAS; PTEN; TP53; Overexpression; Mutation; Microsatellite instability; Complex atypical hyperplasia; Endometrial cancer; Ovarian cancer; cancer; onkologi; Cytologi; cancerology; oncology; Cytology; CNS metastasis; Cytogenetic analysis; BRCA2; BRCA1; B-catenin; CDKN2A;

    Sammanfattning : Endometrial cancer is the most common gynecological cancer diagnosed in western countries. Complex atypical hyperplasia (CAH) reflects a state of hyperestrinism and its role as a precursor lesion of this cancer is established. LÄS MER

  4. 3. Genotypic and phenotypic characterisation of Neisseria gonorrhoeae

    Författare :Magnus Unemo; Bengt Wretlind; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The bacterium Neisseria gonorrhoeae (the gonococcus) is the aetiological agent of gonorrhoea, which remains a major sexually transmitted infection/disease (STI/STD) worldwide. The incidence of gonorrhoea was previously high in many countries, Sweden included. The incidence in Sweden culminated in 1970 with 487 cases per 100,000 inhabitants. LÄS MER

  5. 4. Molecular and functional studies of the BCR/ABL1 fusion gene

    Författare :Petra Johnels; Avdelningen för klinisk genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular fluids; Hematologi; Haematology; onkologi; Cytologi; cancerology; oncology; Cytology; gene expression profiling; acute lymphoblastic leukemia; chronic myeloid leukemia; Ph chromosome; BCR ABL; extracellulära vätskor; Clinical genetics; Klinisk genetik; cancer;

    Sammanfattning : The BCR/ABL1 fusion gene is associated with chronic myeloid leukemia and a subgroup of acute lymphoblastic leukemia. The general aim of this thesis was to increase the understanding of BCR/ABL1-induced leukemogenesis by molecular and functional studies of this fusion gene. LÄS MER

  7. 5. Genetic Variation and Migration of Waders

    Författare :Liv Wennerberg; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mtDNA sequencing; microsatellite analysis; Dunlin; Calidris alpina; Curlew Sandpiper; Calidris ferruginea; White-rumped Sandpiper; Calidris fuscicollis; carbon isotope ratios; Zoologi; Zoology; Ecology; bird migration; population genetics; Ekologi; Animal ecology; Djurekologi;

    Sammanfattning : The migratory behaviour of birds has received much scientific interest, though many questions still remain unsolved. One of the reasons for this is the difficulty of following the birds as they move between breeding and wintering localities. Populations may mix on migration and the origin of individual birds is difficult to assess. LÄS MER