Sökning: "molekylärgenetik"
Visar resultat 6 - 10 av 41 avhandlingar innehållade ordet molekylärgenetik.
6. Functional characterization of interactions between the flavivirus NS5 protein and PDZ proteins of the mammalian host
Sammanfattning : Flaviviruses are found all over the world and affect and infect millions of people every year. Flavivirus infection can lead to severe clinical outcomes resulting in neuronal damages e.g. Tick-borne encephalitis virus (TBEV), or severe hemorrhagic fevers e. LÄS MER
7. Replication Fork Stability in Mammalian Cells
Sammanfattning : Maintaining replication fork integrity is vital to preserve genomic stability and avoid cancer. Physical DNA damage and altered nucleotide or protein pools represent replication obstacles, generating replicative stress. Numerous cellular responses have evolved to ensure faithful DNA replication despite such challenges. LÄS MER
8. Bacterial viruses targeting multi-resistant Klebsiella pneumoniae and Escherichia coli
Sammanfattning : The global increase in antibiotic resistance levels in bacteria is a growing concern to our society and highlights the need for alternative strategies to combat bacterial infections. Bacterial viruses (phages) are the natural predators of bacteria and are as diverse as their hosts, but our understanding of them is limited. LÄS MER
9. Virulence Factors and Motility Mechanisms of Pathogenic Neisseria
Sammanfattning : Neisseria gonorrhoeae and Neisseria meningitidis are two closely related human specific pathogens. Neisseria gonorrhoeae is the causative agent for the sexually transmitted disease gonorrhea and often causes asymptomatic infections in women which is a cause of infertility. LÄS MER
10. The role of MTH1 in ultraviolet radiation-induced mutagenesis
Sammanfattning : Ultraviolet radiation (UVR) is known to be highly mutagenic. What types of DNA lesions that are induced by different UVR wavelengths are still a matter of debate. UVR induces mutagenesis mostly by the formation of photoproducts and the induction of reactive oxygen species (ROS). LÄS MER