Sökning: "molekylärbiologi"

Visar resultat 11 - 15 av 2421 avhandlingar innehållade ordet molekylärbiologi.

  1. 11. Genetic and molecular dissection of hemolymph coagulation and melanization in Drosophila melanogaster

    Författare :Gawa Bidla; Ulrich Theopold; David Schneider; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Molekylärbiologi; Molecular Biology; molekylärbiologi;

    Sammanfattning : Injury to epithelial barriers puts metazoans at risk of loss of body fluid and contamination of their body by foreign particles. This risk is even exacerbated in insects, which have an open circulatory system and as a result, quickly need to seal wounds in order to keep a fairly constant internal milieu. LÄS MER

  3. 12. The p97 ATPase and the Drosophila Proteasome : Protein Unfolding and Regulation

    Författare :Kristian Björk Grimberg; Patrick Young; Neus Visa; Lars Thelander; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; proteasome; ubiquitin; p97; unfolding; regulation; RNAi screen; high-throughput screen; cnc; basic leucine zipper; transcription factors; proteasome inhibition; Molecular biology; Molekylärbiologi; Molecular Biology; molekylärbiologi;

    Sammanfattning : For all living systems, there is a requirement to recycle and regulate proteins. In eukaryotic organisms this is accomplished by the proteasome. The p97 ATPase is another highly conserved and essential complex present throughout the eukaryotic cell. LÄS MER

  4. 13. Type III secretion- the various functions of the translocon operon in bacterial pathogenesis

    Författare :Jeanette E Bröms; Åke Forsberg; Michael Koomey; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Yersinia; Pseudomonas aeruginosa; type III secretion; chaperone; translocation; regulation; lcrGVHyopBD; pcrGVHpopBD; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : In order to establish colonisation of a human host, pathogenic Yersinia use a type III protein secretion system to directly intoxicate host immune cells. Activation of this system requires target cell contact and is a highly regulated process. LÄS MER

  5. 14. Aspects of interferon alpha signalling in hematopoetic cells

    Författare :Lennart Carlsson; erik lundgren; Ulrich Kalinke; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; interferon; human; B-lymphocyte; survival; proliferation; myeloma; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : The type I interferons (IFN) are a family of cytokines with pleiothropic activities that include inhibition of viral replication, cell proliferation and activation of the immune system. These properties give the IFNs important physiological and pathological roles in infection and cancer and have led to their therapeutic use for many clinical conditions. LÄS MER

  7. 15. Quaternary structure and interaction approaches to allosteric regulation of class I ribonucleotide reductases

    Författare :Mikael Crona; Britt-Marie Sjöberg; Mark Meuth; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ribonucleotide reductase; allosteric regulation; quaternary structure; subunit interactions; enzyme activity; SPR; GEMMA; Molecular biology; Molekylärbiologi; Molecular Biology; molekylärbiologi;

    Sammanfattning : Deoxyribonucleic acid (DNA) chains in which our genetic blueprint is stored are built from four DNA precursors by DNA polymerases. The enzyme ribonucleotide reductase (RNR) provides the only de novo synthesis pathway of deoxyribonucleotides from ribonucleotides and is essential for nearly all organisms. LÄS MER