Sökning: "molecular pathology"
Visar resultat 21 - 25 av 264 avhandlingar innehållade orden molecular pathology.
21. Designing a digital pathology workstation for routine practice
Sammanfattning : The role of the pathology lab is important in the future of cancer care. In orderto further personalize the care for cancer patients, more precise review of tumorspecimens is needed in order to guide clinicians between different treatmentstrategies. LÄS MER
22. p53 Alterations in Human Skin : A Molecular Study Based on Morphology
Sammanfattning : Mutation of the p53 gene appears to be an early event in skin cancer development. The present study is based on morphology and represents a cellular and genetic investigation of p53 alterations in normal human skin and basal cell cancer. LÄS MER
23. Minimal Residual Disease Assessment in Childhood Acute Lymphoblastic Leukemia
Sammanfattning : Traditionally, response to treatment in hematological malignancies is evaluated by light microscopy of bone marrow (BM) smears, but due to more effective therapies more sensitive methods are needed. Today, detection of minimal residual disease (MRD) using immunological and molecular techniques can be 100 times more sensitive than morphology. LÄS MER
24. Apolipoprotein A-IV and Transthyretin in Swedish Forms of Systemic Amyloidosis
Sammanfattning : Over 20 different plasma proteins have been shown to have the capacity to undergo conformational changes and self-assemble into highly stable and insoluble amyloid fibrils. One, transthyretin (TTR), consists of 127 amino acid residues arranged in eight β-strands (named A to H) and is involved in two different clinical forms of amyloidosis. LÄS MER
25. The CpG island methylator phenotype in colorectal cancer : studies on risk and prognosis
Sammanfattning : Background Colorectal cancer (CRC) is the second most common malignancy in developed countries. The mortality is high, with nearly half of patients dying from the disease. The primary treatment of CRC is surgery, and decisions about additional treatment with chemotherapy are based mainly on tumor stage. LÄS MER