Sökning: "molecular biomarkers"

Visar resultat 1 - 5 av 301 avhandlingar innehållade orden molecular biomarkers.

  1. 1. Mechanisms in Tendon Healing Pain, Biomarkers and the Role of Mast Cells

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Abdul Alim; Uppsala universitet.; [2019]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tendon Healing; Pain; Biomarkers; Mast Cells; Inflammation; Microdialysis; Neurotransmitters; Glutamate Receptors; Procollagen; Transcriptional factors; Biologi med inriktning mot molekylär immunologi; Biology with specialization in Molecular Immunology; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Neuroscience; Neurovetenskap;

    Sammanfattning : Tendon injuries and tendinopathy are common disorders, but the underlying mechanisms are not well understood. The overall aim of this thesis was to better understand the mechanisms underlying tendon healing, pain, and inflammation. LÄS MER

  2. 2. New Molecular Approaches to Glioblastoma Therapy

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Sathishkumar Baskaran; Uppsala universitet.; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioblastoma; GBM; ZBTB16; PLZF; Heterogeneity; Proteasome inhibitors; Bortezomib; Pterostilbene; drug combinations; Oncology; Onkologi; Biological Research on Drug Dependence; Biologisk beroendeforskning; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Biomedical Laboratory Science; Biomedicinsk laboratorievetenskap; Medicinsk vetenskap; Medical Science; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Glioblastoma (GBM) is the most common high-grade brain tumor diagnosed in patients who are more than 50 years of age. The standard of care treatment is surgery, followed by radiotherapy and chemotherapy. The median life expectancy of patients is only between 12 to 15 months after receiving current treatment regimes. LÄS MER

  3. 3. Insulin Resistance Causes, biomarkers and consequences

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Christoph Nowak; Uppsala universitet.; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; insulin resistance; diabetes; insulin secretion; cardiovascular; mendelian randomization; proteomics; metabolomics; genomics; molecular epidemiology; complex disease; risk prediction; coronary heart disease; stroke; hyperglycemia;

    Sammanfattning : The worldwide increasing number of persons affected by largely preventable diseases like diabetes demands better prevention and treatment. Insulin is required for effective utilisation of circulating nutrients. LÄS MER

  4. 4. The role of gamma-tubulin in cell division and cancer

    Detta är en avhandling från Faculty of Medicine, Translational Medicine, Molecular Pathology

    Författare :Greta Eklund; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Although cancer is a heterogeneous disease, a common theme in tumor cells is the deregulation of cell division, which renders tumor progression independent of otherwise necessary internal or external growth cues. This may provide cancer cells with the ability to divide indefinitely, posing a threat to the rest of the organism. LÄS MER

  5. 5. Translational studies on acute myeloid leukemia focus on the receptor tyrosine kinase FLT3

    Detta är en avhandling från Lund University: Faculty of Medicine

    Författare :Alissa Marhäll; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; [2018]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; AML; FLT3;

    Sammanfattning : Among adults, acute myeloid leukemia (AML) is the second most frequent type of leukemia. In spite of recent improvements in the treatment of this disease, a majority of patients develop drug resistance, leading to poor overall survival. One of the factors behind this is mutations in the tyrosine kinase receptor (FLT3). LÄS MER