Sökning: "moieties"

Visar resultat 1 - 5 av 138 avhandlingar innehållade ordet moieties.

  1. 1. Synthesis of indole and oxindole derivates incorporating pyrrolidino, pyrrolo or imidazolo moieties

    Författare :Stanley Rehn; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Isatin; three-component reaction; a-amino acid; azomethine ylide; pyrrolidino-3-spiro-3?-oxindole derivatives; 3-methyleneoxindole derivatives; pyrroloquinolone; TosMIC; ß-carboline; tosylimine; pyrrole; keto-enol tautomerism; indolopyran-2-one; imidazole; benzylimine; tetrahydroindole;

    Sammanfattning : The focus of this thesis is on the synthesis of oxindole- and indole-derivatives incorporating pyrrolidins, pyrroles or imidazoles moieties. Pyrrolidino-2-spiro-3'-oxindole derivatives have been prepared in high yielding three-component reactions between isatin, alpha-amino acid derivatives, and suitable dipolarophiles. LÄS MER

  3. 2. Structural diversity of the lipid A and core oligosaccharide moieties of the lipopolysaccharides from nontypeable and serotype f Haemophilus influenzae

    Författare :Håkan H. Yildirim; Elke Schweda; Andrzej Gamian; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Haemophilus influenzae; LPS; biosynthesis; NMR; ESI-MS;

    Sammanfattning : This thesis describes structural studies of the oligosaccharide and lipid A moieties of lipopolysaccharides (LPSs) isolated from disease-causing Haemophilus influenzae strains. The nontypeable strains were clinical isolates from the middle ear of children suffering from otitis media and the serotype f strains had been collected from three adults with respiratory tract infections. LÄS MER

  4. 3. Metal‐Free Arylations of Oxygen and Nitrogen Nucleophiles : Applications of Diaryliodonium Salts

    Författare :Elin Stridfeldt; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; arylation; aryloxyamines; cyclization; diaryliodonium salts; O-aryloximes; sigmatropic rearrangement;

    Sammanfattning : This thesis concerns development of new methods for metal‐free arylations in organic synthesis. The protocols discussed in the thesis are based on a class of hypervalent iodine compounds called diaryliodonium salts. These reagents are known to transfer aryl moieties to suitable nucleophiles. LÄS MER

  5. 4. Improving Tröger's Base Chemistry : Developing the Chemistry of Tröger's base

    Författare :Sami Dawaigher; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Tröger’s base; Host Guest Chemistry; Metalation; Computational Chemistry; Supramolecular Chemistry;

    Sammanfattning : The Tröger’s base framework has been implemented in two different receptors. The first of these receptors, incorporating two 18-crown-6 moities, was used as a host in a binding study together with a sieries of bisammonium salts that yielded different binding constants that were then used as a benchmark to compare different computational methods (Molecular Mechanics (MM) and Density Functional Theory (DFT)) in predicting the correct results where the MM methods proved more effective. LÄS MER

  7. 5. Coordination of Phosphine-Thioether Ligands to Low-valent Metal Centers

    Författare :Roger Persson; Kemisk fysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; polynuclear metal complexes; fluxional behavior; cluster; thioether; phosphine; crystal structure; sulfur; triosmium;

    Sammanfattning : The reactivity of the phosphine-thioether ligands bis(2-diphenylphosphino) ethylthio)ethane (PSSP), bis(2-(diphenylphosphino) ethyl)sulfane (PSP), PPh2CH2CH2SMe (PS), PPh2(o-C6H4SMe (PortoS), and PPh(o-C6H4SMe)2 (PSS) towards low-valent carbonyl clusters has been studied. In all structurally characterized clusters, the ligand donor atoms are terminally coordinated. LÄS MER