Sökning: "modified drug release"

Visar resultat 21 - 25 av 29 avhandlingar innehållade orden modified drug release.

  1. 21. Relating the Bulk and Interface Structure of Hyaluronan to Physical Properties of Future Biomaterials

    Författare :Ida Berts; Jöns Hilborn; Adrian R Rennie; Giovanna Fragneto; John W White; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; hyaluronan; structure; bulk; interface; small-angle neutron scattering; neutron reflection; hydrogel; grafting; nanoparticles; protein interactions;

    Sammanfattning : This dissertation describes a structural investigation of hyaluronan (HA) with neutron scattering techniques. HA is a natural biopolymer and one of the major components of the extracellular matrix, synovial fluid, and vitreous humor. LÄS MER

  3. 22. Hemicelluloses from Agricultural and Forestry Crops Isolation, Characterisation, and Enzymatic Hydrolysis

    Författare :Alexandra Andersson; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Proteiner; enzymologi; Physical chemistry; Fysikalisk kemi; enzymology; hydrogels; Plant biochemistry; Växtbiokemi; Proteins; a-galactosidase; b-mannanase; hemicellulase; corn fibre; barley husks; spruce; size-exclusion chromatography; arabinoxylan; microwave irradiation; steam pretreatment; membrane filtration; hemicellulose; galactoglucomannan;

    Sammanfattning : Hemicelluloses are tremendous sources of renewable raw materials, which utilisation have the potential to be highly increased in the future. Hemicelluloses are among the major groups of compounds in plant cell walls, together with cellulose and lignin. These three components are closely associated, making them difficult to separate from each other. LÄS MER

  4. 23. Experimental studies on novel pharmacological strategies in the treatment of schizophrenia

    Författare :Amani Eltayb; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Schizophrenia; L-dopa; topiramate; 5-HT2C; citalopram; WAY 100635; CAR; catalepsy;

    Sammanfattning : The modified dopamine (DA) hypothesis of schizophrenia suggests a hyperdopaminergic state in subcortical brain regions, which is believed to cause positive symptoms, while cortical regions may show a hypodopaminergic state which is believed to generate negative and cognitive symptoms. Positive symptoms are improved by typical antipsychotic drug (APD) treatment. LÄS MER

  5. 24. Purine and Pyrazolopyrimidine Derivatives: Design and Synthesis of Chemical Tools for Biological Applications

    Författare :David Bliman; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; purine; pyrazolopyrimidine; caged compounds; protein kinases; protein-protein interactions; fluorescence; organic synthesis;

    Sammanfattning : Purines can be found in a multitude of naturally occurring compounds with a range of functions. This thesis describes the design and synthesis of purines and structurally related pyrazolopyrimidine derivatives intended for biological applications. LÄS MER

  7. 25. Tunable and modular assembly of polypeptides and polypeptide-hybrid biomaterials

    Författare :Christopher Aronsson; Daniel Aili; Karin Enander; Staffan Dånmark; Dennis Löwik; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Biomaterials are materials that are specifically designed to be in contact with biological systems and have for a long time been used in medicine. Examples of biomaterials range from sophisticated prostheses used for replacing outworn body parts to ordinary contact lenses. Currently it is possible to create biomaterials that can e.g. LÄS MER