Avancerad sökning
Visar resultat 1 - 5 av 29 avhandlingar som matchar ovanstående sökkriterier.
1. Water-swelling tablets based on hydrophobically modified poly(acrylic acid) - Effects of amphiphiles on swelling and drug release
Sammanfattning : An important issue within the pharmaceutical world today is the increasing number of poorly soluble drugs. These often show a low bioavailability and a susceptibility to varying conditions in the intestine. LÄS MER
2. Ethyl Cellulose Membranes used in Modified Release Formulations
Sammanfattning : Ethyl cellulose (EC) is a commonly used polymer in modified drug release formulations. The general aim of the present study was to investigate release mechanisms through non-porous EC membranes with hydroxypropyl methyl cellulose (HPMC) contents ranging from 0 to 30% by weight. LÄS MER
3. Preparation of Tablets from Reservoir Pellets with an Emphasis on the Compression Behaviour and Drug Release
Sammanfattning : The preparation of multiple unit tablets was investigated in this thesis with the intention of gaining a deeper understanding of some of the factors that influence the properties of such tablets.Initially, three different types of pellets (drug, soft and disintegrant pellets) were combined as a model to investigate the ability of the mixture to form disintegrating tablets. LÄS MER
4. Multifunctional Glyconanomaterials : Applications in Biorecognition and Drug Delivery
Sammanfattning : This thesis consists of three parts, which revolve around the fabrication of multifunctional glyconanomaterials (cellulose nanocrystals, chitin nanocrystals, mesoporous silica nanoparticles) and the development of their applications in biorecognition and nanomedicine.Part one presents a detailed introduction to glyconanomaterials, focusing on cellulose nanocrystals, chitin nanocrystals and mesoporous silica nanoparticles, including their general preparations, properties and applications. LÄS MER
5. Nanoparticles for multifunctional drug delivery systems
Sammanfattning : Multifunctional drug delivery systems incorporated with stimuli-sensitive drug release, magnetic nanoparticles and magnetic resonance (MR) T2 contrast agents is attracting increasing attention recently. In this thesis, works on polymer nanospheres response to temperature change, superparamagnetic iron oxide nanoparticles (SPION)/polymeric composite materials for MR imaging contrast agents are summarized. LÄS MER