Sökning: "mode of CCR5 use"
Hittade 2 avhandlingar innehållade orden mode of CCR5 use.
1. Recombinant CXCR4/CCR5 hybrid receptors as tools for studies of HIV-1 receptor usage
Sammanfattning : The chemokine receptors CCR5 and CXCR4 are required, together with CD4, for the entry of HIV-1 into target cells. CCR5 using HIV-1 dominates during transmission and the asymptomatic phase of infection. During progression, virus phenotypes with the ability to use CXCR4 emerge in about 50% of infected individuals. LÄS MER
2. Virus tropism and neutralization response in SIV infection
Sammanfattning : Simian immunodeficiency virus (SIV) infections in macaques are commonly used as models to study the pathogenesis of human immunodeficiency virus (HIV). Both SIV and HIV normally use the CD4 receptor and an additional coreceptor for cell entry. The most common coreceptors used by HIV are CCR5 and CXCR4. LÄS MER