Sökning: "mitogen-activated protein kinase"

Visar resultat 6 - 10 av 95 avhandlingar innehållade orden mitogen-activated protein kinase.

  1. 6. Changes in mitogen-activated protein kinase phosphorylation and inorganic phosphate induced by skeletal muscle contraction

    Författare :Charlott Wretman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Skeletal muscle; MAP kinase; signal transduction; contraction; acute exercise; exercise intensity; fibre-type; concentric; ROS; eccentric.;

    Sammanfattning : Skeletal muscles adjust to the level of contractile activity by different biochemical alterations. Contraction is a multifactorial stimulus with short-term metabolic effects and long-term responses due to changes in protein synthesis. LÄS MER

  3. 7. Protein Kinase Inhibition in Late Cerebral Ischemia after Subarachnoid Hemorrhage

    Författare :Saema Ansar; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurology; neuropsychology; neurophysiology; Neurologi; protein kinase; cerebral ischemia; subarachnoid hemorrage; neurofysiologi; neuropsykologi;

    Sammanfattning : The cerebral ischemia that occur after a subarachnoid hemorrhage (SAH) often results in death or severe disability and is a significant cause of stroke. Our hypothesis is that cerebral ischemia leads to pathophysiological receptor changes on the vascular smooth muscle cells. LÄS MER

  4. 8. Effects of Ischaemia on the Neuroretina and Retinal Blood Vessels

    Författare :Bodil Gesslein; Lund Oftalmologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein kinase C; tumor necrosis factor; mitogen-activated protein kinases; pig; blood vessels; mfERG; Retinal ischaemia; vascular endothelial growth factor; hypoxia-inducible factor;

    Sammanfattning : Identification of the intracellular signal transduction pathways activated in retinal ischaemia may be important in revealing novel pharmacological targets. The retinal blood vessels are key organs in circulatory failure, and in this work the retinal vasculature was therefore examined separately from the neuroretina. LÄS MER

  5. 9. Signalling to Activation of Cytosolic Phospholipase A2 and Arachidonate Release in Macrophages

    Författare :Gösta Hiller; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; signal transduction; dexamethasone; macrophages; phospholipase C; phosphatidylinositol 3-kinase; mitogen-activated protein kinases; cytosolic phospholipase A2; arachidonic acid; Histology; cytochemistry; histokemi; cytokemi; tissue culture; Histologi; vävnadskultur; histochemistry;

    Sammanfattning : Eicosanoids include prostaglandins, thromboxanes and leukotrienes, which are arachidonic acid oxygenation products. These lipids make important contributions to the signs and symptoms of inflammatory diseases. LÄS MER

  7. 10. Effects of adenosine and acetylcholine on the lacrimal gland

    Författare :Stina K. Carlsson; J. Peter Gierow; Sven Tågerud; Darlene Dartt; Linnéuniversitetet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Lacrimal gland; adenosine; adenosine receptors; signal transduction; exocrine secretion; tear film; dry eye; Sjögren’s syndrome; acetylcholine; mitogen activated protein kinase; p38; Cell biology; Cellbiologi; Ophtalmology; Oftalmologi; Cell and molecular biology; Cell- och molekylärbiologi; Cell biology; Cellbiologi; Molecular biology; Molekylärbiologi; Biomedical Sciences; Biomedicinsk vetenskap;

    Sammanfattning : A balanced tear film is essential for a healthy ocular surface. Insufficient tear production may result in dry eye, a common disorder in the elderly population. Dry eye causes significant discomfort in the patients and may lead to visual impairment and ocular infections. LÄS MER