Sökning: "mitogen-activated protein kinase"
Visar resultat 11 - 15 av 95 avhandlingar innehållade orden mitogen-activated protein kinase.
11. MAPK and pro-inflammatory mediators in the walls of brain blood vessels following cerebral ischemia
Sammanfattning : INTRODUCTION Stroke is a serious neurological disease which may lead to death and severe disability [1, 2]. There are two major types of stroke: ischemic and hemorrhagic stroke. LÄS MER
12. Mechanisms for TGF-β-Mediated Regulation of the Actin Filament System and Apoptosis
Sammanfattning : Transforming growth factor-β (TGF-β) is a member of a large superfamily of cytokines which participate in many different types of cellular processes, such as growth inhibition, cell migration, differentiation, cell adhesion, wound healing and immunosuppression. Alterations of TGF-β superfamily signalling results in several different disorders, including bone disease, vascular disease and cancer. LÄS MER
13. Hyperglycemia and Focal Brain Ischemia : Clinical and Experimental Studies
Sammanfattning : Diabetes is a major risk factor for ischemic stroke and is associated with increased mortality. Additionally, hyperglycemia, a common complication in acute stroke, is associated with poor outcome. LÄS MER
14. Calcium calmodulin-dependent protein kinase signal transduction in cerebral arteries
Sammanfattning : Cerebral arteries participate actively in the response that follows an episode of cerebral ischemia in man and rat. It has been shown that the vascular endothelin receptor expression is increased in stroke and organ culture. LÄS MER
15. Regeneration of Peripheral Nerves. The role of protein kinases, with emphasis on neurotrophic factor stimulation
Sammanfattning : The purpose of this study was to investigate the role of protein kinases in peripheral nerve regeneration, with the use of dorsal root ganglia (DRG) and nodose ganglia explants from adult mice. The effects of neurotrophic factor stimulation and protein kinase inhibition were studied for long (days) and short term (minutes) effects. LÄS MER