Sökning: "mitogen activated protein kinase"

Visar resultat 11 - 15 av 99 avhandlingar innehållade orden mitogen activated protein kinase.

  1. 11. Calcium calmodulin-dependent protein kinase signal transduction in cerebral arteries

    Författare :Roya Waldsee; Lund Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CAMK; Ednothelin receptors; Calcium; gene regulation;

    Sammanfattning : Cerebral arteries participate actively in the response that follows an episode of cerebral ischemia in man and rat. It has been shown that the vascular endothelin receptor expression is increased in stroke and organ culture. LÄS MER

  2. 12. Effects of adenosine and acetylcholine on the lacrimal gland

    Författare :Stina K. Carlsson; J. Peter Gierow; Sven Tågerud; Darlene Dartt; Linnéuniversitetet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Lacrimal gland; adenosine; adenosine receptors; signal transduction; exocrine secretion; tear film; dry eye; Sjögren’s syndrome; acetylcholine; mitogen activated protein kinase; p38; Cell biology; Cellbiologi; Ophtalmology; Oftalmologi; Cell and molecular biology; Cell- och molekylärbiologi; Cell biology; Cellbiologi; Molecular biology; Molekylärbiologi; Biomedical Sciences; Biomedicinsk vetenskap;

    Sammanfattning : A balanced tear film is essential for a healthy ocular surface. Insufficient tear production may result in dry eye, a common disorder in the elderly population. Dry eye causes significant discomfort in the patients and may lead to visual impairment and ocular infections. LÄS MER

  3. 13. MAPK and pro-inflammatory mediators in the walls of brain blood vessels following cerebral ischemia

    Författare :Aida Maddahi; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mitogen activated protein kinase; iNOS; Matrix metalloproteinases; IL-1ß; IL-6; TNF-α; Inflammation; Subarachnoid hemorrhage; Middle cerebral artery occlusion;

    Sammanfattning : INTRODUCTION Stroke is a serious neurological disease which may lead to death and severe disability [1, 2]. There are two major types of stroke: ischemic and hemorrhagic stroke. LÄS MER

  4. 14. Regeneration of Peripheral Nerves. The role of protein kinases, with emphasis on neurotrophic factor stimulation

    Författare :Peter Wiklund; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NT-4; NT-3; NGF; MAPK; PKG; PKA; PKC; nodose ganglion; DRG; conditioning effect; neurotrophic factors; protein kinases; peripheral; nerve regeneration; BDNF; GDNF; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : The purpose of this study was to investigate the role of protein kinases in peripheral nerve regeneration, with the use of dorsal root ganglia (DRG) and nodose ganglia explants from adult mice. The effects of neurotrophic factor stimulation and protein kinase inhibition were studied for long (days) and short term (minutes) effects. LÄS MER

  5. 15. The role of glucocorticoid receptors and mitogen-regulated protein kinases in the cochlea

    Författare :Inna Meltser; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Hearing loss induced by acoustic trauma is a common handicap for the human population. Acoustic trauma triggers a cascade of changes in the cochlea such as a direct mechanical damage of sensory hair cells, biochemical disturbances including reactive oxygen and nitrogen species generation, release of pro-inflammatory cytokines and exitotoxicity. LÄS MER