Sökning: "mitochondrial membrane potential"
Visar resultat 16 - 20 av 77 avhandlingar innehållade orden mitochondrial membrane potential.
16. Mitochondrial form and function in pancreatic β-cells and brown adipocytes
Sammanfattning : This thesis is focused on the role of mitochondria in pancreatic β-cells and brown adipose tissue (BAT). Two main aspects of mitochondria were explored; mitochondrial functional efficiency and the interrelationship between mitochondrial shape and function. LÄS MER
17. The Role of Mitochondrial Uncoupling in the Development of Diabetic Nephropathy
Sammanfattning : Diabetes is closely associated with increased oxidative stress, especially originating from the mitochondria. A mechanism to reduce increased mitochondria superoxide production is to reduce the mitochondria membrane potential by releasing protons across the mitochondria membrane. LÄS MER
18. Mitochondrial function in human skeletal muscle: with special reference to exercise and training
Sammanfattning : The overall objective of this thesis was to study the adaptation of oxidative function in human skeletal muscle to acute exercise of different modes, intensities and durations, and to endurance training. The effects of endurance training on mitochondrial function were evaluated in cross-sectional and longitudinal studies by measurements of mitochondrial oxygen consumption in isolated mitochondria and permeabilised muscle fibres and measurements of mitochondrial ATP production rate in isolated mitochondria. LÄS MER
19. Studies on the structure and biogenesis of membrane proteins from the green alga Chlamydomonas reinhardtii
Sammanfattning : The green alga unicellular Chlamydomonas reinhardtii has been used for many years as a model system in the area of photosynthesis. Therefore, the C. reinhardtii chloroplast has been the subject of many studies. In contrast, the mitochondria have received less attention. LÄS MER
20. Calcium-induced mitochondrial permeability transition in CNS-derived mitochondria - Pharmacological aspects of specificity and toxicity in neuroprotection
Sammanfattning : Mitochondria are the main site for energy conversion in the cell. Under certain circumstances, such as excess calcium retention or production of reactive oxygen species, a pore forms at contact sites between the outer and the normally impermeable inner mitochondrial membrane. LÄS MER