Sökning: "mitochondrial genome"
Visar resultat 1 - 5 av 121 avhandlingar innehållade orden mitochondrial genome.
1. Mitochondrial Evolution : Turning Bugs into Features
Sammanfattning : The bacterial origin of mitochondria from an ancient endosymbiosis is now widely accepted and the mitochondrial ancestor is generally believed to belong to the bacterial subdivision α-proteobacteria. The high fraction of mitochondrial proteins encoded in the nucleus has commonly been explained with a massive transfer of genes from the genome of the ancestral mitochondrion. LÄS MER
2. Mitochondrial translation and its impact on protein homeostasis and aging
Sammanfattning : Besides their famous role as powerhouse of the cell, mitochondria are also involved in many signaling processes and metabolism. Therefore, it is unsurprising that mitochondria are no isolated organelles but are in constant crosstalk with other parts of the cell. LÄS MER
3. The interactome of the yeast mitochondrial ribosome : Organization of mitochondrial post-transcriptional regulation, membrane protein insertion and quality control
Sammanfattning : The proteins found in mitochondria originate from two different genetic systems. Most mitochondrial proteins are synthesized in the cytosol and post-translationally imported into the organelle. However, a small subset of mitochondrial proteins is encoded in an organelle-resident genome. LÄS MER
4. Phylogeny and topological incongruence in the Rubioideae (Rubiaceae)
Sammanfattning : The work with this thesis has focused on evolutionary relationships in the Rubioideae, the most species-rich subfamily of the large and diverse coffee family (Rubiaceae). Despite considerable efforts during the last decades, uncertainty regarding several relationships in this group has remained, either as a result of unconvincing statistic support, incongruent results, or insufficient taxon sampling. LÄS MER
5. Mitochondrial Genome Analysis Using Next Generation Sequencing for Forensic Applications
Sammanfattning : Mitochondrial DNA (mtDNA) analysis plays a specialized role in forensic applications, overcoming certain limitations of autosomal DNA markers. The high copy number and uniparental inheritance pattern of mtDNA are advantageous in cases involving shed hairs and aged skeletal elements, especially decades-old missing persons cases. LÄS MER