Sökning: "mitochondrial genes"

Visar resultat 21 - 25 av 214 avhandlingar innehållade orden mitochondrial genes.

  1. 21. Exercise-induced mitochondrial biogenesis : with special reference to mitochondrial transcription factors and lipin-1

    Författare :Susanna E Wallman Appel; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mitochondrial biogenesis is one prominent adaptation to endurance training in skeletal muscle tissue. An increased mitochondrial density of the muscle fibres contributes to an enhanced aerobic capacity and thereby to improved fatigue-resistance. LÄS MER

  3. 22. Organization of mitochondrial gene expression in yeast : Specific features of organellar protein synthesis

    Författare :Kirsten Kehrein; Martin Ott; Thomas A Fox; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; translation; bc1 complex; ribosome; gene expression; Biochemistry; biokemi;

    Sammanfattning : Mitochondria contain their own genetic system, encoding key subunits of the oxidative phosphorylation system. These subunits are expressed by an organelle-specific gene expression machinery. LÄS MER

  4. 23. The metabolic syndrome : studies on thrifty genes

    Författare :Katja Kannisto; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Adipose tissue; adiponectin; 11beta-hydroxysteroid dehydrogenase type 1; BMI; glucocorticoid; GLUT; HAART; HIV; IL-6; insulin; insulin resistance; LDL-cholesterol; leptin; lifestyle; lipodystrophy; LPL; obesity; PPAR; PGC-1; polymorphism; rosiglitazone; skeletal muscle; twins;

    Sammanfattning : The metabolic syndrome consists of a cluster of atherogenic risk factors that include insulin resistance, glucose intolerance, hyperglycemia, dyslipidemia, obesity and a procoagulant state with impaired fibrinolysis. Genetic factors might predispose to the metabolic syndrome while the increasing prevalence of visceral and abdominal obesity linked to the shift to more sedentary lifestyles exacerbates the manifestation. LÄS MER

  5. 24. Mitochondrial dysfunction and the metabolism - studies on respiratory chain disorders

    Författare :Nikica Tomasic; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mitochondria; mitochondrial disease; metabolism; complex III; BCS1L;

    Sammanfattning : Background: Mutations of the mitochondrial assembly factor BCS1L disrupt assembly and function of the respiratory chain complex III (CIII) and thereby result in energy deprivation. In GRACILE syndrome, the BCS1L mutation causes a liver disorder that leads to metabolic disturbances associated with severe growth restriction. LÄS MER

  7. 25. Studies of nuclear encoded mitochondrial proteins in metabolism

    Författare :Qian Zhao; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mitochondrial function is vital for human health. Inherited genetic disease can cause mitochondrial DNA (mtDNA) deficiency, disorders with generally poor prognosis. The majority of the genesinvolved in keeping a normal mitochondrial function are nuclear encoded. LÄS MER