Sökning: "mitochondrial gene expression"

Visar resultat 21 - 25 av 156 avhandlingar innehållade orden mitochondrial gene expression.

1. 21. Gene silencing mechanisms in Phytophthora infestans

   Författare :Vetukuri Ramesh; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
   Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

   Sammanfattning : The hemibiotrophic oomycete, Phytophthora infestans, causes late blight on potato and tomato. This destructive pathogen is well known for the rapidity with which it overcomes host resistance. This thesis focuses on the molecular basis of gene (RNA) silencing in P. infestans and the role it may have in its genome biology and pathogenesis. LÄS MER

3. 22. Acute myeloid leukemia : apoptotic signalling and gene expression associated with treatment response

   Författare :Marita Lagergren Lindberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Acute myeloid leukemia (AML) is a severe, life threatening malignancy characterized by a clonal expansion of immature myeloid cells in the bone marrow, resulting in severe infections and bleedings. High dose chemotherapy is able to normalize the blood and bone marrow morphology (complete remission, CR) in a majority of treated patients, but recurrent disease, typically occurs within 1-2 years. LÄS MER

4. 23. From gene mutation to gene expression : studies on multiple endocrine neoplasia type 1 and vascular endothelial growth factors

   Författare :Emma Tham; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Multiple endocrine neoplasia type 1; mutation detection; Vascular Endothelial Growth Factors; recombinant protein; dilated cardiomyopathy; multiple sclerosis;

   Sammanfattning : Multiple Endocrine Neoplasia type 1, MEN1, is an inherited cancer syndrome whose gene was localised to chromosome 11q13 in 1988. A number of !candidate genes were characterised before the MEN1 gene was cloned in 1997. DNA sequencing of MEN1 to search for mutations in patients is used as a complement to clinical diagnosis. LÄS MER

5. 24. Mitochondrial RNA processing in health and disease

   Författare :Isabelle Laine; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Mitochondria are often described as the powerhouses of the cell, providing the main cellular energy source in the form of adenosine triphosphate. Five enzyme complexes, collectively termed the oxidative phosphorylation system, use the reducing power from nutrients to synthesise adenosine triphosphate via cellular respiration. LÄS MER

7. 25. Mitochondrial dysfunction in ageing and degenerative disease

   Författare :Anna Wredenberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The cytoplasm of eukaryotic cells contains a dynamic network of double-membraned organelles, called mitochondria, which perform the process of oxidative phosphorylation (OXPHOS) that provides cellular energy in the form of ATP. The respiratory chain creates an electrochemical gradient across the inner mitochondrial membrane, which drives ATP synthesis by the ATP synthase. LÄS MER