Sökning: "mitochondrial biogenesis"

Visar resultat 6 - 10 av 57 avhandlingar innehållade orden mitochondrial biogenesis.

  1. 6. Training-induced increase in mitochondrial biogenesis

    Författare :Emma Hawke; Department of Neurological and Movement Sciences University of Verona; []
    Nyckelord :alkalosis; acidosis; muscle adaptation; PGC1alpha; cell signalling;

    Sammanfattning : Endurance training leads to an improved ability of muscle to utilize oxygen. This is related to an increased density and function of mitochondria. LÄS MER

  3. 7. Organization and regulation of mitochondrial gene expression

    Författare :Roger Salvatori; Martin Ott; Benoit Kornmann; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; mitochondrial gene expression; post-transcriptional regulation; mitochondrial ribosome; protein-protein proximity; BioID; feedback loop; Biochemistry; biokemi;

    Sammanfattning : Mitochondria possess their own genome, remnant of the ancestral eubacterial endosymbiont DNA. This mitochondrial genome encodes mostly few key subunits of the respiratory chain. In order to synthesize these few proteins, mitochondria contain a complete gene expression machinery. LÄS MER

  4. 8. Mechanistic Insights in the Biogenesis and Function of the Respiratory Chain

    Författare :Hannah Dawitz; Martin Ott; Cristina Ugalde; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; respiratory chain; bc1 complex; cytochrome c oxidase; Cbp3; Rcf1; Rcf2; respiratory supercomplexes; biogenesis; mitochondria; Saccharomyces cerevisiae; Biochemistry; biokemi;

    Sammanfattning : Mitochondria fulfill a plethora of functions, including harboring metabolic pathways and converting energy stored in metabolites into ATP, the common energy source of the cell. This last function is performed by the oxidative phosphorylation system, consisting of the respiratory chain and the ATP synthase. LÄS MER

  5. 9. Interconnectivity of mitochondrial protein biogenesis and homeostasis

    Författare :Carmela Vázquez Calvo; Martin Ott; Jan Riemer; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mitochondria; proteostasis; protein quality control; chaperones; biokemi; Biochemistry;

    Sammanfattning : To ensure correct protein function, the cells are equipped with a tightly regulated network of chaperones that support protein folding and actively participate in protein quality control (PQC) and turnover. Due to the dual origin of the mitochondrial proteome, the cytosolic and mitochondrial PQC networks coordinate to ensure protein import and assembly in the organelle. LÄS MER

  7. 10. Thyroid hormone regulation of mammalian mitochondrial biogenesis

    Författare :Vigg Joste; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER