Sökning: "mismatch repair protein expression"
Visar resultat 11 - 15 av 18 avhandlingar innehållade orden mismatch repair protein expression.
11. Embryonic and adult cardiac stem cells : molecular, electrophysical and immunological characteristics for cardiac repair
Sammanfattning : Background: The concept of myocardial regeneration by means of stimulating the endogenous regenerative potential in situ is an attractive approach. This offers distinct advantages to stem cell implantation where the problems with engraftment and immune rejection are avoided. LÄS MER
12. Molecular alterations in colorectal cancer
Sammanfattning : Colorectal cancer is one of the most common causes to death due to cancer in the world. It is important to understand the molecular mechanisms behind tumour development for both prognostic and therapeutic applications. LÄS MER
13. Phospholipase C β3, and its role in endocrine tumorigenesis
Sammanfattning : The Phospholipase C β3 (PLCB3) gene is located on chromosome 11q13, in the vicinity of theMultiple Endocrine Neoplasia type 1 (MEN1) suppressor gene. PLCB3 has been implicated inendocrine tumorigenesis based on findings of low expression in endocrine tumors, and the probableexistence of other suppressor genes located at 11q13. LÄS MER
14. Prognostic and predictive biomarkers in metastatic colorectal cancer constant and evolutionary perspectives
Sammanfattning : Colorectal cancer (CRC) affects nearly 2 million people each year and accounts for 900 000 deaths worldwide. The main prognostic factor is disease stage at diagnosis and around 40% of the patients presents with or develop metastatic CRC (mCRC). LÄS MER
15. Biomarkers in pancreatic and other periampullary cancers - some familiar and one new
Sammanfattning : AbstractBackground: Adenocarcinomas arising in the area around the papilla of Vater are referred to as periampullary adenocarcinomas and are of four different anatomical origins: pancreas, distal bile duct, ampulla and duodenum. These heterogeneous tumors are usually divided into two morphological subtypes, pancreatobiliary type (PB-type) and intestinal type (I-type), which provides more important prognostic information than tumor origin. LÄS MER