Sökning: "mimicry"

Visar resultat 16 - 20 av 45 avhandlingar innehållade ordet mimicry.

  1. 16. Evolution and viral mimicry of short linear motif-mediated interactions

    Författare :Filip Mihalič; Per Jemth; Leo James; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; phage display; protein-protein interactions; large-scale discovery; short linear motifs; viral mimcry; viral hijacking; Biokemi; Biochemistry; Medical Biochemistry; Medicinsk biokemi;

    Sammanfattning : Proteins are one of the most fundamental building blocks of life and their interactions regulate every cellular process. Historically they have been conceptualized as predominantly folded entities with well-defined secondary and tertiary structures. LÄS MER

  3. 17. Alopecia and vitiligo in autoimmune polyendocrine syndrome type I

    Författare :Håkan Hedstrand; Uppsala universitet; []
    Nyckelord :Medical sciences; APS I; autoantigen; vitiligo; alopecia areata; cDNA-library; immunoscreening; tyrosine hydroxylase; SOX9; SOX10; molecular mimicry; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : Autoimmune polyendocrine syndrome type I (APS I) is a recessively inherited disease caused by mutations in a recently identified gene, AIRE, on human chromosome 21. APS I patients are affected by autoimmune destruction of multiple endocrine glands and other organs as well as ectodermal structures. LÄS MER

  4. 18. Murine B lymphocyte growth regulation : a study of host defence factors and their mimicry by Mycoplasma arginini

    Författare :Erik Ruuth; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B lymphocyte; growth; lymphokine; lymphokine-like; host-parasite; M. arginini; membrane acyl protein;

    Sammanfattning : Immune responses are the result of extended clonal growth and maturation of specific precursors preexisting in low frequencies. Clonal expansion is partly controlled by soluble factors, thus, their identification is essential for the understanding of the immune response regulation. LÄS MER

  5. 19. Creating creation : readings of Pasternak's Doktor Živago

    Författare :Susanna Witt; Boris Gasparov; Stockholms universitet; []
    Nyckelord :Pasternak; Boris Leonidovič; Doktor Zhivago;

    Sammanfattning : This study investigates the process of creation in Boris Pasternak's Doktor Îivago (1957), both as depicted in and as realized by the novel. Statements on art, on literature in general and on specific texts are found to have a bearing on the novel itself, thus providing clues to its own poetics and philosophy of art.Ch. LÄS MER

  7. 20. Synthesis of O-linked Carbasugar Analogues of Galactofuranosides and N-linked Neodisaccharides

    Författare :Jens Frigell; Ian Cumpstey; George Fleet; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; carbasugar; galactofuranose; mycobacterium; tuberculosis; ring-closing metathesis; GlfT2; galactan; epoxide-opening; pseudodisaccharide; etherification; regioselective; carbohydrate; carbocycles; glycomimetics; glucosidase; neodisaccharides; Mitsunobu; Organic synthesis; Organisk syntes; organisk kemi; Organic Chemistry;

    Sammanfattning : In this thesis, carbohydrate mimicry is investigated through the syntheses of carbohydrate analogues and evaluation of their inhibitory effects on carbohydrate-processing enzymes. Galactofuranosides are interesting structures because they are common motifs in pathogenic microorganisms but not found in mammals. M. LÄS MER