Sökning: "microfluidic"

Visar resultat 16 - 20 av 206 avhandlingar innehållade ordet microfluidic.

  1. 16. Microfluidic bead-based methods for DNA analysis

    Författare :Aman Russom; Ulf Gyllensten; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; single nucleotide polymorphism; DNA analysis; SNP; microfluidics; pyrosequencing; beads; lab on a chip; hybridization; DASH; microsystem; micro totat analysis system; allele-specific extension; DASH; microcontact printing; Genetik; Clinical genetics; Klinisk genetik;

    Sammanfattning : With the completion of the human genome sequencing project, attention is currently shifting toward understanding how genetic variation, such as single nucleotide polymorphism (SNP), leads to disease. To identify, understand, and control biological mechanisms of living organisms, the enormous amounts of accumulated sequence information must be coupled to faster, cheaper, and more powerful technologies for DNA, RNA, and protein analysis. LÄS MER

  3. 17. Microfluidic and Molecular Tools for Genetic Analyses

    Författare :Henrik Johansson; Mats Nilsson; Ivo Gut; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microfluidics; PCR; sequencing; cancer genetics; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; Medical Genetics; Medicinsk genetik;

    Sammanfattning : Methods that enable interrogation of multiple genomic regions in parallel are very useful for efficient detection of genetic variation. Two different types of probes are described in this thesis that can be used for direct analysis or for sample preparation upstream of Next Generation Sequencing. LÄS MER

  4. 18. Ultrasonic Handling of Living Cells in Microfluidic Systems

    Författare :Jessica Svennebring; Martin Wiklund; Hans Hertz; Martyn Hill; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Bioengineering; Bioteknik;

    Sammanfattning : Microfluidic chips have become a powerful tool in research where biological cells are processed and/or analyzed. One method for contactless cell manipulation in microfluidic chips that has gained an increasing amount of attention the last decade is ultrasonic standing wave (USW) technology. LÄS MER

  5. 19. Microfluidic electrocapture technology in protein and peptide analysis

    Författare :Juan Astorga-Wells; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : After sequencing the genomes of several organisms, science in the postgenomic era now aims at a thorough study of the proteins present in a given tissue or organism. Since this task requires an enormous analytical effort, integrated microfluidic systems are envisioned as the solution to automated high throughput analysis of biomolecules. LÄS MER

  7. 20. Microfluidic blood sample preparation for rapid sepsis diagnostics

    Författare :Jonas Hansson; Hjalmar Brismar; Aman Russom; Fredrik Nikolajeff; KTH; []
    Nyckelord :3D fluidic networks; bacteria isolation; inertial microfluidics; lab-on-chip; microfluidics; particle filtration; PDMS membrane; selective cell lysis. sepsis;

    Sammanfattning : Sepsis, commonly referred to as blood poisoning, is a serious medical condition characterized by a whole-body inflammatory state caused by microbial infection. Rapid treatment is crucial, however, traditional culture-based diagnostics usually takes 2-5 days. LÄS MER