Sökning: "microfluidic dilution"

Hittade 4 avhandlingar innehållade orden microfluidic dilution.

  1. 1. The Multifunctional Pipette. A Microfluidic Technology for the Biosciences

    Författare :Alar Ainla; Chalmers University of Technology; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; microfluidic superfusion; microfluidic temperature sensing.; microfluidic dilution; hydrodynamic flow confinement; microfluidic mixer; supported lipid membranes; single-cell analysis; Microfluidics; microfabrication; PDMS;

    Sammanfattning : The theme of the work described in this thesis is the generation and application of liquid microenvironments in chemistry and bioscience using microfluidic devices. First, a computer controlled multi-stage dilution system to generate time-dependent chemical waves was developed, and its application was demonstrated on model biomembranes. LÄS MER

  2. 2. On methods for probing structure and function of membrane proteins

    Författare :Erik Jansson; Chalmers University of Technology; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; proteomics; patch-clamp; mass spectrometry.; proteoliposomes; microfluidic superfusion; cholesterol; TRPV1; limited proteolysis; Membrane proteins; fluorescence;

    Sammanfattning : The determination of structure–function relationships in membrane proteins plays a key role for the understanding of molecular mechanisms in biological systems, and may provide information on how these systems can be modulated by pharmaceuticals. The aim of the work described herein was to develop methods for studying structure and function of membrane proteins, ideally in combination. LÄS MER

  3. 3. Novel microfluidic based sample preparation methods for rapid separation and detection of viable bacteria from blood for sepsis diagnostics

    Författare :Sharath Narayana Iyengar; Aman Russom; Jonas Tegenfeldt; KTH; []
    Nyckelord :microfluidics; Bioteknologi; Biotechnology;

    Sammanfattning : Sepsis is a serious medical condition characterized by a whole-body inflammatory response caused by bloodstream infection. The final stage of sepsis can lead to septic shock, multiple organ failure, and death. In early sepsis, the concentration of bacteria in the bloodstream is typically low, making diagnosis challenging. LÄS MER

  4. 4. Clinical applications of acoustophoresis in blood based diagnostics

    Författare :Klara Petersson; Avdelningen för Biomedicinsk teknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Acoustophoresis; Acoustofluidics; Ultrasound; Microfluidics; Blood; Blood Separation; Blood plasma; Lab-on-a-chip; Point-of-care; Blood diagnostics;

    Sammanfattning : In this thesis, acoustofluidics has been used to process blood samples as a sample preparation step prior to biomarker detection. This is often required as the large amount of blood cells otherwise can interfere with the detection method. Acoustofluidics means moving particles or cells with acoustic forces within microfluidic channels. LÄS MER