Sökning: "microenvironment"

Visar resultat 6 - 10 av 376 avhandlingar innehållade ordet microenvironment.

  1. 6. Growth factor signaling in the breast tumor microenvironment

    Författare :Matteo Bocci; Avdelningen för translationell cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; Tumor microenvironment; Angiogenesis; Cancer-associated fibroblasts; PDGF-C; ALK1;

    Sammanfattning : Cancer represents a collection of malignancies characterized by an aberrant expansion of cells. This unrestrained growth is the result of the acquisition of several pro-survival features and the evasion of cellular fail-safe mechanisms, collectively known as the hallmarks of cancer. LÄS MER

  3. 7. Molecular characterization of the immune microenvironment in melanoma

    Författare :Rita Cabrita; Melanoma Genomics; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Melanoma; Immune microenvironment; Tertiary lymphoid structures; Immunotherapy; Immune evasion; Methylation; Immune gene signatures;

    Sammanfattning : .... LÄS MER

  4. 8. Inflammatory Cells and Mediators in the Tumor Microenvironment of Breast Cancer

    Författare :Roni Allaoui; Malmö Cancerimmunologi; []
    Nyckelord :Breast cancer; tumor stroma; cancer-associated fibroblasts; DAMP; inflammatory mediators; myeloid-derived supressor cells; toll-like receptors; triple-negative breast cancer; tumor infiltrating lymphocytes; tumor microenvironment;

    Sammanfattning : .... LÄS MER

  5. 9. Cancer and Therapy: A look into stemness and the tumour microenvironment

    Författare :Carmen Rodriguez; Avdelningen för translationell cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; COMP; STRIPAK; Notch; p21; oncofetal chondroitin sulfate; therapy; tumour microenvironment;

    Sammanfattning : Therapy is the often-used treatment for cancer patients, even those that undergo resection surgery. While milestones have been surpassed throughout the decades for a number of cancer types, there are those that comprise of characteristics limiting effectiveness of treatments. LÄS MER

  7. 10. Implantation-Site Dependent Differences in Engraftment and Function of Transplanted Pancreatic Islets

    Författare :Joey Lau; Per-Ola Carlsson; Leif Jansson; Carina Carlsson; Caroline Kampf; Annika Tibell; Uppsala universitet; []
    Nyckelord :Cell biology; Type 1 diabetes; pancreatic islets; human islets; islet transplantation; vascular engraftment; revascularization; implantation-site; microenvironment; vascular density; insulin release; pro insulin biosynthesis; glucose oxidation; Cellbiologi;

    Sammanfattning : Transplanting pancreatic islets into the liver through the portal vein is currently the most common procedure in clinical islet transplantations for treating patients with brittle type 1 diabetes. However, most islet grafts fail within a 5-year period necessitating retransplantation. LÄS MER