Sökning: "microenvironment"
Visar resultat 11 - 15 av 376 avhandlingar innehållade ordet microenvironment.
11. Prognostic Markers in Diffuse Large B-cell Lymphoma : How Bad can it be
Sammanfattning : Diffuse large B-cell lymphoma (DLBCL), which is the most common type of lymphoma, is characterised by its aggressiveness and poor outcome without adequate treatment and also for its biological and clinical heterogeneity. It is therefore highly desirable to gain a more profound understanding of the underlying biology of the disease, as well as predictive factors for the guidance of treatment. LÄS MER
12. Lipases at interfaces
Sammanfattning : Lipases are acyl hydrolases that play a key role in fat digestion by cleaving long-chain triglycerides into polar lipids. Due to an opposite polarity between the enzyme (is hydrophilic) and their substrates (are lipophilic), the lipase reaction occurs at the interface between the aqueous and the oil phases. LÄS MER
13. Immunologic Markers in the Tumor Microenvironment of Classical Hodgkin Lymphoma
Sammanfattning : In classical Hodgkin lymphoma (cHL), cytokine regulation and cellular composition of the tumor microenvironment (TME) is crucial for tumor cell survival. In paper I, we examined the presence of CD138+ plasma cells and IgG4+ plasma cells in diagnostic cHL biopsies with immunohistochemistry (IHC). LÄS MER
14. The impact of the progranulin-sortilin axis on breast cancer stem cell activity and patient outcome
Sammanfattning : Breast cancer is the most common cancer in women worldwide. Still today, despite current breast cancer therapies, many patients experience treatment resistance and relapse, which are believed to be due to failure in targeting treatment-resistant cancer stem cells. LÄS MER
15. Hodgkin Lymphoma in children, adolescents and young adults
Sammanfattning : Hodgkin lymphoma (HL) is a heterogeneous condition varying from engaging one single lymph node site to a widespread condition. The prognosis with contemporary treatment is excellent for the vast majority. However, the treatment might cause severe late adverse effects in a proportion of the affected individuals. LÄS MER